Exceptionally elevated triglyceride in severe lipemia retinalis
Han Y Yin,1–3 Roberto Warman,2,4 Edward H Suh,2 Anny MS Cheng2,3 1Wayne State University, School of Medicine, Detroit, MI, 2Department of Ophthalmology, Florida International University, Herbert Wertheim College of Medicine, 3Ocular Surface Center, Miami, 4Division of Pediatric Ophthalmolo...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Dove Medical Press
2016-10-01
|
| Series: | International Medical Case Reports Journal |
| Subjects: | |
| Online Access: | https://www.dovepress.com/exceptionally-elevated-triglyceride-in-severe-lipemia-retinalis-peer-reviewed-article-IMCRJ |
| _version_ | 1818021376132382720 |
|---|---|
| author | Yin HY Warman R Suh EH Cheng AM |
| author_facet | Yin HY Warman R Suh EH Cheng AM |
| author_sort | Yin HY |
| collection | DOAJ |
| description | Han Y Yin,1–3 Roberto Warman,2,4 Edward H Suh,2 Anny MS Cheng2,3 1Wayne State University, School of Medicine, Detroit, MI, 2Department of Ophthalmology, Florida International University, Herbert Wertheim College of Medicine, 3Ocular Surface Center, Miami, 4Division of Pediatric Ophthalmology, Nicklaus Children’s Hospital, Miami, FL, USA Purpose: To report a case of successful treatment for severe lipemia retinalis with extreme severe hypertriglyceridemia (sHTG).Design: Observational case report.Observations: A 6-week-old infant with severe lipemia retinalis manifested diffuse creamy retinal vessels complicated with vulvar xanthomas. Extreme sHTG with 185-folds of the normal level was reported. Chromosome microarray and lipid gene sequencing confirmed a homozygous lipoprotein lipase gene coding mutation.Results: Under strict adherence to a high medium-chain triglycerides formula and discontinuation of breast milk, the lipemia retinalis and vulval lesions resolved along with a stable plasma lipid level throughout the follow-up period of 6 months.Conclusion: Strict adherence to a low-fat diet without breast milk appears to be effective in treating infants with severe lipemia retinalis associated with exceptionally high triglycerides. Keywords: hypertriglyceride, infant, lipemia retinalis, lipoprotein lipase gene |
| first_indexed | 2024-04-14T08:17:08Z |
| format | Article |
| id | doaj.art-2164eef62dd647fc8ad1eae9e7e6445d |
| institution | Directory Open Access Journal |
| issn | 1179-142X |
| language | English |
| last_indexed | 2024-04-14T08:17:08Z |
| publishDate | 2016-10-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | International Medical Case Reports Journal |
| spelling | doaj.art-2164eef62dd647fc8ad1eae9e7e6445d2022-12-22T02:04:21ZengDove Medical PressInternational Medical Case Reports Journal1179-142X2016-10-01Volume 933333629564Exceptionally elevated triglyceride in severe lipemia retinalisYin HYWarman RSuh EHCheng AMHan Y Yin,1–3 Roberto Warman,2,4 Edward H Suh,2 Anny MS Cheng2,3 1Wayne State University, School of Medicine, Detroit, MI, 2Department of Ophthalmology, Florida International University, Herbert Wertheim College of Medicine, 3Ocular Surface Center, Miami, 4Division of Pediatric Ophthalmology, Nicklaus Children’s Hospital, Miami, FL, USA Purpose: To report a case of successful treatment for severe lipemia retinalis with extreme severe hypertriglyceridemia (sHTG).Design: Observational case report.Observations: A 6-week-old infant with severe lipemia retinalis manifested diffuse creamy retinal vessels complicated with vulvar xanthomas. Extreme sHTG with 185-folds of the normal level was reported. Chromosome microarray and lipid gene sequencing confirmed a homozygous lipoprotein lipase gene coding mutation.Results: Under strict adherence to a high medium-chain triglycerides formula and discontinuation of breast milk, the lipemia retinalis and vulval lesions resolved along with a stable plasma lipid level throughout the follow-up period of 6 months.Conclusion: Strict adherence to a low-fat diet without breast milk appears to be effective in treating infants with severe lipemia retinalis associated with exceptionally high triglycerides. Keywords: hypertriglyceride, infant, lipemia retinalis, lipoprotein lipase genehttps://www.dovepress.com/exceptionally-elevated-triglyceride-in-severe-lipemia-retinalis-peer-reviewed-article-IMCRJHyper-triglycerideInfantLipemia Retinalis |
| spellingShingle | Yin HY Warman R Suh EH Cheng AM Exceptionally elevated triglyceride in severe lipemia retinalis International Medical Case Reports Journal Hyper-triglyceride Infant Lipemia Retinalis |
| title | Exceptionally elevated triglyceride in severe lipemia retinalis |
| title_full | Exceptionally elevated triglyceride in severe lipemia retinalis |
| title_fullStr | Exceptionally elevated triglyceride in severe lipemia retinalis |
| title_full_unstemmed | Exceptionally elevated triglyceride in severe lipemia retinalis |
| title_short | Exceptionally elevated triglyceride in severe lipemia retinalis |
| title_sort | exceptionally elevated triglyceride in severe lipemia retinalis |
| topic | Hyper-triglyceride Infant Lipemia Retinalis |
| url | https://www.dovepress.com/exceptionally-elevated-triglyceride-in-severe-lipemia-retinalis-peer-reviewed-article-IMCRJ |
| work_keys_str_mv | AT yinhy exceptionallyelevatedtriglycerideinseverelipemiaretinalis AT warmanr exceptionallyelevatedtriglycerideinseverelipemiaretinalis AT suheh exceptionallyelevatedtriglycerideinseverelipemiaretinalis AT chengam exceptionallyelevatedtriglycerideinseverelipemiaretinalis |