Cysteine and iron accelerate the formation of ribose-5-phosphate, providing insights into the evolutionary origins of the metabolic network structure.
The structure of the metabolic network is highly conserved, but we know little about its evolutionary origins. Key for explaining the early evolution of metabolism is solving a chicken-egg dilemma, which describes that enzymes are made from the very same molecules they produce. The recent discovery...
Main Authors: | Gabriel Piedrafita, Sreejith J Varma, Cecilia Castro, Christoph B Messner, Lukasz Szyrwiel, Julian L Griffin, Markus Ralser |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2021-12-01
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Series: | PLoS Biology |
Online Access: | https://doi.org/10.1371/journal.pbio.3001468 |
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