ZIKV infection effects changes in gene splicing, isoform composition and lncRNA expression in human neural progenitor cells

ZIKV infection effects changes in gene splicing, isoform composition and lncRNA expression in human neural progenitor cells

Abstract Background The Zika virus (ZIKV) is a mosquito-borne flavivirus that causes microcephaly and Guillain-Barré syndrome in infected individuals. To obtain insights into the mechanism of ZIKV infection and pathogenesis, we analyzed the transcriptome of ZIKV infected human neural progenitor cell...

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Bibliographic Details
Main Authors: Benxia Hu, Yongxia Huo, Liping Yang, Guijun Chen, Minhua Luo, Jinlong Yang, Jumin Zhou
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Virology Journal
Subjects:
lncRNA
Gene isoform
Alternative splicing
hNPC
ZIKV
Online Access:http://link.springer.com/article/10.1186/s12985-017-0882-6

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