Multistate model for pharmacometric analyses of overall survival in HER2‐negative breast cancer patients treated with docetaxel
Abstract The aim of this study was to develop a multistate model for overall survival (OS) analysis, based on parametric hazard functions and combined with an investigation of predictors derived from a longitudinal tumor size model on the transition hazards. Different states – stable disease, tumor...
Main Authors: | Sreenath M. Krishnan, Lena E. Friberg, René Bruno, Ulrich Beyer, Jin Y. Jin, Mats O. Karlsson |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2021-10-01
|
Series: | CPT: Pharmacometrics & Systems Pharmacology |
Online Access: | https://doi.org/10.1002/psp4.12693 |
Similar Items
-
Bayesian forecasting of tumor size metrics and overall survival
by: Sreenath M. Krishnan, et al.
Published: (2022-12-01) -
A multistate modeling and simulation framework to learn dose–response of oncology drugs: Application to bintrafusp alfa in non‐small cell lung cancer
by: Han Liu, et al.
Published: (2023-11-01) -
Dr. Hartmut Derendorf, PhD, a world‐renowned expert in pharmacokinetics and pharmacometrics (1953–2020)
by: Vikram Sinha, et al.
Published: (2021-06-01) -
Metaheuristics for pharmacometrics
by: Seongho Kim, et al.
Published: (2021-11-01) -
CPT: Pharmacometrics & Systems Pharmacology – Inception, Maturation, and Future Vision
by: Karen Rowland Yeo, et al.
Published: (2021-07-01)