POST MORTEM CHANGES: CHALLENGES IN DRUG ANALYSIS IN THE DIAGNOSIS OF DEATHS FROM INTOXICATION
In forensic toxicology, alternative matrices and sampling sites are required for a correlation of antemortem and postmortem concentrations with the least possible error. Postmortem redistribution phenomena and biochemical changes inherent to these processes are possible, and represent interferences...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Universidade Federal do Rio Grande do Sul
2021-06-01
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| Series: | Drug Analytical Research |
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| Online Access: | https://seer.ufrgs.br/dar/article/view/111711/63353 |
| _version_ | 1819117266113921024 |
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| author | Marina Camargo Galera Luciana Grazziotin Rossato-Grando |
| author_facet | Marina Camargo Galera Luciana Grazziotin Rossato-Grando |
| author_sort | Marina Camargo Galera |
| collection | DOAJ |
| description | In forensic toxicology, alternative matrices and sampling sites are required for a correlation of antemortem and postmortem concentrations with the least possible error. Postmortem redistribution phenomena and biochemical changes inherent to these processes are possible, and represent interferences in these analyses. This study aimed to perform a bibliographic review through Pubmed database within a 10-year period of time, using the keywords: forensic analysis AND redistribution. We observed that for quantitative analyses the preferred matrix is blood from peripheral vessels, and when it is not available, vitreous humor is a great specimen for choice. |
| first_indexed | 2024-12-22T05:30:15Z |
| format | Article |
| id | doaj.art-216a0d00e28a4ffcb9a4aadaa485da07 |
| institution | Directory Open Access Journal |
| issn | 2527-2616 |
| language | English |
| last_indexed | 2024-12-22T05:30:15Z |
| publishDate | 2021-06-01 |
| publisher | Universidade Federal do Rio Grande do Sul |
| record_format | Article |
| series | Drug Analytical Research |
| spelling | doaj.art-216a0d00e28a4ffcb9a4aadaa485da072022-12-21T18:37:29ZengUniversidade Federal do Rio Grande do SulDrug Analytical Research2527-26162021-06-01511418https://doi.org/10.22456/2527-2616.111711POST MORTEM CHANGES: CHALLENGES IN DRUG ANALYSIS IN THE DIAGNOSIS OF DEATHS FROM INTOXICATIONMarina Camargo Galera0Luciana Grazziotin Rossato-Grando1Universidade de Passo FundoUniversidade de Passo FundoIn forensic toxicology, alternative matrices and sampling sites are required for a correlation of antemortem and postmortem concentrations with the least possible error. Postmortem redistribution phenomena and biochemical changes inherent to these processes are possible, and represent interferences in these analyses. This study aimed to perform a bibliographic review through Pubmed database within a 10-year period of time, using the keywords: forensic analysis AND redistribution. We observed that for quantitative analyses the preferred matrix is blood from peripheral vessels, and when it is not available, vitreous humor is a great specimen for choice.https://seer.ufrgs.br/dar/article/view/111711/63353postmortem redistributiontoxicological analysessampling sitevitreous humorforensic toxicology |
| spellingShingle | Marina Camargo Galera Luciana Grazziotin Rossato-Grando POST MORTEM CHANGES: CHALLENGES IN DRUG ANALYSIS IN THE DIAGNOSIS OF DEATHS FROM INTOXICATION Drug Analytical Research postmortem redistribution toxicological analyses sampling site vitreous humor forensic toxicology |
| title | POST MORTEM CHANGES: CHALLENGES IN DRUG ANALYSIS IN THE DIAGNOSIS OF DEATHS FROM INTOXICATION |
| title_full | POST MORTEM CHANGES: CHALLENGES IN DRUG ANALYSIS IN THE DIAGNOSIS OF DEATHS FROM INTOXICATION |
| title_fullStr | POST MORTEM CHANGES: CHALLENGES IN DRUG ANALYSIS IN THE DIAGNOSIS OF DEATHS FROM INTOXICATION |
| title_full_unstemmed | POST MORTEM CHANGES: CHALLENGES IN DRUG ANALYSIS IN THE DIAGNOSIS OF DEATHS FROM INTOXICATION |
| title_short | POST MORTEM CHANGES: CHALLENGES IN DRUG ANALYSIS IN THE DIAGNOSIS OF DEATHS FROM INTOXICATION |
| title_sort | post mortem changes challenges in drug analysis in the diagnosis of deaths from intoxication |
| topic | postmortem redistribution toxicological analyses sampling site vitreous humor forensic toxicology |
| url | https://seer.ufrgs.br/dar/article/view/111711/63353 |
| work_keys_str_mv | AT marinacamargogalera postmortemchangeschallengesindruganalysisinthediagnosisofdeathsfromintoxication AT lucianagrazziotinrossatogrando postmortemchangeschallengesindruganalysisinthediagnosisofdeathsfromintoxication |