Case report: Multiple epstein-barr virus-associated smooth muscle tumours in a child with IL-2-inducible T-cell kinase mutation of undetermined clinical significance

Case report: Multiple epstein-barr virus-associated smooth muscle tumours in a child with IL-2-inducible T-cell kinase mutation of undetermined clinical significance

BackgroundEBV-associated smooth muscle tumours (EBV-SMTs) are uncommon neoplasms associated with immunodeficiency. The pathogenesis of EBV-SMTs is poorly understood. IL-2-inducible T-cell kinase (ITK), a member of the Tec family of tyrosine kinases, is the predominant Tec kinase in T cells. Research...

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Bibliographic Details
Main Authors: Qiongli Wen, Jing Ning, Zhiqun Mao, Xiangdang Long, Xiangling He, Zhihong Chen, Qiuyi Di, Qiaorong Li, Yu Zhuo, Gang Zhong
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Pediatrics
Subjects:
IL-2-inducible t-cell kinase
mutation
gene
epstein-Barr virus
smooth muscle tumour
immunodeficiency
Online Access:https://www.frontiersin.org/articles/10.3389/fped.2023.1189219/full

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