Bilateral acute retinal necrosis caused by two separate viral etiologies
Purpose: To describe an unusual case of bilateral acute retinal necrosis (ARN) that was caused by varicella zoster virus in one eye and Epstein-Barr virus in the fellow eye. Observations: A 67-year-old immunocompromised man presented with ARN in the left eye following a dermatomal vesicular rash, wi...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2020-06-01
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| Series: | American Journal of Ophthalmology Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2451993619300751 |
| _version_ | 1818693377455030272 |
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| author | Andrew M. Williams Vincent Q. Nguyen Benjamin W. Botsford Andrew W. Eller |
| author_facet | Andrew M. Williams Vincent Q. Nguyen Benjamin W. Botsford Andrew W. Eller |
| author_sort | Andrew M. Williams |
| collection | DOAJ |
| description | Purpose: To describe an unusual case of bilateral acute retinal necrosis (ARN) that was caused by varicella zoster virus in one eye and Epstein-Barr virus in the fellow eye. Observations: A 67-year-old immunocompromised man presented with ARN in the left eye following a dermatomal vesicular rash, with an aqueous sample positive for varicella zoster virus. Four months later, the patient presented with panuveitis and serous retinal detachment in the right eye, with vitreous sample positive for Epstein-Barr virus and negative for varicella zoster, herpes simplex, and cytomegalovirus. Conclusions and importance: We report a rare case of bilateral ARN with independent infection of each eye by different viruses; varicella zoster in the left eye and, four months later, Epstein-Barr virus in the right eye. Immunocompromised patients are vulnerable to ARN from any of its inciting viral causes, and intraocular fluid should be obtained for diagnostic confirmation from the second eye in cases of bilateral ARN. |
| first_indexed | 2024-12-17T13:12:43Z |
| format | Article |
| id | doaj.art-2179b08fd48141259e83096a2850928e |
| institution | Directory Open Access Journal |
| issn | 2451-9936 |
| language | English |
| last_indexed | 2024-12-17T13:12:43Z |
| publishDate | 2020-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | American Journal of Ophthalmology Case Reports |
| spelling | doaj.art-2179b08fd48141259e83096a2850928e2022-12-21T21:47:05ZengElsevierAmerican Journal of Ophthalmology Case Reports2451-99362020-06-0118Bilateral acute retinal necrosis caused by two separate viral etiologiesAndrew M. Williams0Vincent Q. Nguyen1Benjamin W. Botsford2Andrew W. Eller3Retina Service, Department of Ophthalmology, University of Pittsburgh Medical Center, 203 Lothrop Street, Pittsburgh, PA, USARetina Service, Department of Ophthalmology, University of Pittsburgh Medical Center, 203 Lothrop Street, Pittsburgh, PA, USARetina Service, Department of Ophthalmology, University of Pittsburgh Medical Center, 203 Lothrop Street, Pittsburgh, PA, USACorresponding author. Eye and Ear Institute, 8th floor, 203 Lothrop Street, Pittsburgh, PA, 15213, USA.; Retina Service, Department of Ophthalmology, University of Pittsburgh Medical Center, 203 Lothrop Street, Pittsburgh, PA, USAPurpose: To describe an unusual case of bilateral acute retinal necrosis (ARN) that was caused by varicella zoster virus in one eye and Epstein-Barr virus in the fellow eye. Observations: A 67-year-old immunocompromised man presented with ARN in the left eye following a dermatomal vesicular rash, with an aqueous sample positive for varicella zoster virus. Four months later, the patient presented with panuveitis and serous retinal detachment in the right eye, with vitreous sample positive for Epstein-Barr virus and negative for varicella zoster, herpes simplex, and cytomegalovirus. Conclusions and importance: We report a rare case of bilateral ARN with independent infection of each eye by different viruses; varicella zoster in the left eye and, four months later, Epstein-Barr virus in the right eye. Immunocompromised patients are vulnerable to ARN from any of its inciting viral causes, and intraocular fluid should be obtained for diagnostic confirmation from the second eye in cases of bilateral ARN.http://www.sciencedirect.com/science/article/pii/S2451993619300751Acute retinal necrosisVaricella zoster virusEpstein-barr virusPosterior uveitisInfectious uveitis |
| spellingShingle | Andrew M. Williams Vincent Q. Nguyen Benjamin W. Botsford Andrew W. Eller Bilateral acute retinal necrosis caused by two separate viral etiologies American Journal of Ophthalmology Case Reports Acute retinal necrosis Varicella zoster virus Epstein-barr virus Posterior uveitis Infectious uveitis |
| title | Bilateral acute retinal necrosis caused by two separate viral etiologies |
| title_full | Bilateral acute retinal necrosis caused by two separate viral etiologies |
| title_fullStr | Bilateral acute retinal necrosis caused by two separate viral etiologies |
| title_full_unstemmed | Bilateral acute retinal necrosis caused by two separate viral etiologies |
| title_short | Bilateral acute retinal necrosis caused by two separate viral etiologies |
| title_sort | bilateral acute retinal necrosis caused by two separate viral etiologies |
| topic | Acute retinal necrosis Varicella zoster virus Epstein-barr virus Posterior uveitis Infectious uveitis |
| url | http://www.sciencedirect.com/science/article/pii/S2451993619300751 |
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