A case of intracranial hemorrhage in a neonate with congenital factor VII deficiency
Congenital factor VII deficiency is a rare autosomal-recessive bleeding disorder. Bleeding manifestations and clinical findings vary widely, ranging from asymptomatic subjects to patients with hemorrhages that may cause significant handicaps. Treatment has traditionally involved factor VII(FVII) rep...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Korean Pediatric Society
2010-10-01
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| Series: | Korean Journal of Pediatrics |
| Subjects: | |
| Online Access: | http://kjp.or.kr/upload/pdf/kjped-53-913.pdf |
| _version_ | 1818266014987583488 |
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| author | Won Seok Lee Young Sil Park |
| author_facet | Won Seok Lee Young Sil Park |
| author_sort | Won Seok Lee |
| collection | DOAJ |
| description | Congenital factor VII deficiency is a rare autosomal-recessive bleeding disorder. Bleeding manifestations and clinical findings vary widely, ranging from asymptomatic subjects to patients with hemorrhages that may cause significant handicaps. Treatment has traditionally involved factor VII(FVII) replacement therapy using fresh frozen plasma, prothrombin complex concentrates or plasma-derived FVII concentrates. Recombinant activated FVII (NovoSeven®) is currently considered the first-line treatment for replacement therapy of FVII deficiency. Here we present a case of severe intracerebral and intraventricular hemorrhage in a neonate with congenital FVII deficiency. |
| first_indexed | 2024-12-12T19:59:58Z |
| format | Article |
| id | doaj.art-217c0affbc7347bc9cb94b22981377ee |
| institution | Directory Open Access Journal |
| issn | 1738-1061 2092-7258 |
| language | English |
| last_indexed | 2024-12-12T19:59:58Z |
| publishDate | 2010-10-01 |
| publisher | Korean Pediatric Society |
| record_format | Article |
| series | Korean Journal of Pediatrics |
| spelling | doaj.art-217c0affbc7347bc9cb94b22981377ee2022-12-22T00:13:47ZengKorean Pediatric SocietyKorean Journal of Pediatrics1738-10612092-72582010-10-01531091391610.3345/kjp.2010.53.10.9132010531008A case of intracranial hemorrhage in a neonate with congenital factor VII deficiencyWon Seok Lee0Young Sil Park1Department of Pediatrics, Kyung Hee University School of Medicine, Seoul, Korea.Department of Pediatrics, Kyung Hee University School of Medicine, Seoul, Korea.Congenital factor VII deficiency is a rare autosomal-recessive bleeding disorder. Bleeding manifestations and clinical findings vary widely, ranging from asymptomatic subjects to patients with hemorrhages that may cause significant handicaps. Treatment has traditionally involved factor VII(FVII) replacement therapy using fresh frozen plasma, prothrombin complex concentrates or plasma-derived FVII concentrates. Recombinant activated FVII (NovoSeven®) is currently considered the first-line treatment for replacement therapy of FVII deficiency. Here we present a case of severe intracerebral and intraventricular hemorrhage in a neonate with congenital FVII deficiency.http://kjp.or.kr/upload/pdf/kjped-53-913.pdfCongenital factor VII deficiencyIntracranial hemorrhageNeonate |
| spellingShingle | Won Seok Lee Young Sil Park A case of intracranial hemorrhage in a neonate with congenital factor VII deficiency Korean Journal of Pediatrics Congenital factor VII deficiency Intracranial hemorrhage Neonate |
| title | A case of intracranial hemorrhage in a neonate with congenital factor VII deficiency |
| title_full | A case of intracranial hemorrhage in a neonate with congenital factor VII deficiency |
| title_fullStr | A case of intracranial hemorrhage in a neonate with congenital factor VII deficiency |
| title_full_unstemmed | A case of intracranial hemorrhage in a neonate with congenital factor VII deficiency |
| title_short | A case of intracranial hemorrhage in a neonate with congenital factor VII deficiency |
| title_sort | case of intracranial hemorrhage in a neonate with congenital factor vii deficiency |
| topic | Congenital factor VII deficiency Intracranial hemorrhage Neonate |
| url | http://kjp.or.kr/upload/pdf/kjped-53-913.pdf |
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