Sex-specific role of galectin-3 in aortic stenosis

Sex-specific role of galectin-3 in aortic stenosis

Abstract Background Aortic stenosis (AS) is characterized by inflammation, fibrosis, osteogenesis and angiogenesis. Men and women develop these mechanisms differently. Galectin-3 (Gal-3) is a pro-inflammatory and pro-osteogenic lectin in AS. In this work, we aim to analyse a potential sex-differenti...

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Bibliographic Details
Main Authors: Lara Matilla, Ernesto Martín-Núñez, Mattie Garaikoetxea, Adela Navarro, Ibai Tamayo, Amaya Fernández-Celis, Alicia Gainza, Joaquín Fernández-Irigoyen, Enrique Santamaría, Pieter Muntendam, Virginia Álvarez, Rafael Sádaba, Eva Jover, Natalia López-Andrés
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Biology of Sex Differences
Subjects:
Galectin-3
Aortic stenosis
Sex differences
Valve interstitial cell
Inflammation
Calcification
Online Access:https://doi.org/10.1186/s13293-023-00556-1

Internet

https://doi.org/10.1186/s13293-023-00556-1

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