Comparative Efficacy of Velopharyngeal Surgery Techniques for Obstructive Sleep Apnea: A Systematic Review

<i>Background</i><b>:</b> In recent years, surgical interventions for obstructive sleep apnea (OSA) have evolved rapidly, with numerous techniques described in the literature. The approach to velopharyngeal surgery for obstructive sleep apnea has transformed over time, shifti...

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Main Authors: Ana Maria Vlad, Cristian Dragos Stefanescu, Iemima Stefan, Viorel Zainea, Razvan Hainarosie
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Medicina
Subjects:
Online Access:https://www.mdpi.com/1648-9144/59/6/1147
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author Ana Maria Vlad
Cristian Dragos Stefanescu
Iemima Stefan
Viorel Zainea
Razvan Hainarosie
author_facet Ana Maria Vlad
Cristian Dragos Stefanescu
Iemima Stefan
Viorel Zainea
Razvan Hainarosie
author_sort Ana Maria Vlad
collection DOAJ
description <i>Background</i><b>:</b> In recent years, surgical interventions for obstructive sleep apnea (OSA) have evolved rapidly, with numerous techniques described in the literature. The approach to velopharyngeal surgery for obstructive sleep apnea has transformed over time, shifting from an aggressive removal of redundant excess soft tissue to less invasive reconstruction techniques that aim to preserve pharyngeal function while effectively managing sleep apnea. This review aims to evaluate and compare the efficacy of the surgical techniques utilized for OSA at the level of the palate and pharynx. It will cover both traditional and novel procedures. <i>Methods:</i> A comprehensive search of the major databases, such as PubMed/MEDLINE, Web of Science, and Scopus, was conducted to identify the relevant literature. We included articles written in English that analyzed the outcomes of adult patients who received velopharyngeal surgery for sleep apnea. Only comparative studies that examined at least two techniques were considered. <i>Results:</i> In all of the studies combined, the total number of patients who underwent velopharyngeal surgery was 614 in eight studies. All surgical procedures resulted in improvements in the apnea–hypopnea index (AHI). The highest success rates and best outcomes were achieved by barbed reposition pharyngoplasty (BRP) in most studies, ranging from 64.29% to 86.6%. BRP also demonstrated the most significant improvements in both objective and subjective parameters closely followed by ESP that obtained similar efficiency in some studies, especially when combined with anterior palatoplasty (AP), but with a higher incidence of complications. While LP showed moderate efficiency compared with BRP or ESP, the UPPP techniques exhibited greater outcome variability among studies, with a success rate ranging from 38.71% to 59.26%, and the best results observed in a multilevel context. <i>Conclusions:</i> In our review, BRP was the most preferred, effective, and safe among all velopharyngeal techniques, closely followed by ESP. However, older described techniques also showed good results in well-selected patients. Larger-scale studies, preferably prospective, that rigorously incorporate DISE-based strict inclusion criteria might be needed to assess the efficacy of different techniques and generalize the findings.
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spelling doaj.art-2181197f09f64f4c9ec373f432464f322023-11-18T11:32:10ZengMDPI AGMedicina1010-660X1648-91442023-06-01596114710.3390/medicina59061147Comparative Efficacy of Velopharyngeal Surgery Techniques for Obstructive Sleep Apnea: A Systematic ReviewAna Maria Vlad0Cristian Dragos Stefanescu1Iemima Stefan2Viorel Zainea3Razvan Hainarosie4“Prof. Dr. Dorin Hociota” Institute of Phonoaudiology and Functional ENT Surgery, 21st Mihail Cioranu Street, 061344 Bucharest, Romania“Prof. Dr. Dorin Hociota” Institute of Phonoaudiology and Functional ENT Surgery, 21st Mihail Cioranu Street, 061344 Bucharest, RomaniaENT Department, Faculty of Medicine, “Carol Davila” University of Medicine and Pharmacy, 030167 Bucharest, Romania“Prof. Dr. Dorin Hociota” Institute of Phonoaudiology and Functional ENT Surgery, 21st Mihail Cioranu Street, 061344 Bucharest, Romania“Prof. Dr. Dorin Hociota” Institute of Phonoaudiology and Functional ENT Surgery, 21st Mihail Cioranu Street, 061344 Bucharest, Romania<i>Background</i><b>:</b> In recent years, surgical interventions for obstructive sleep apnea (OSA) have evolved rapidly, with numerous techniques described in the literature. The approach to velopharyngeal surgery for obstructive sleep apnea has transformed over time, shifting from an aggressive removal of redundant excess soft tissue to less invasive reconstruction techniques that aim to preserve pharyngeal function while effectively managing sleep apnea. This review aims to evaluate and compare the efficacy of the surgical techniques utilized for OSA at the level of the palate and pharynx. It will cover both traditional and novel procedures. <i>Methods:</i> A comprehensive search of the major databases, such as PubMed/MEDLINE, Web of Science, and Scopus, was conducted to identify the relevant literature. We included articles written in English that analyzed the outcomes of adult patients who received velopharyngeal surgery for sleep apnea. Only comparative studies that examined at least two techniques were considered. <i>Results:</i> In all of the studies combined, the total number of patients who underwent velopharyngeal surgery was 614 in eight studies. All surgical procedures resulted in improvements in the apnea–hypopnea index (AHI). The highest success rates and best outcomes were achieved by barbed reposition pharyngoplasty (BRP) in most studies, ranging from 64.29% to 86.6%. BRP also demonstrated the most significant improvements in both objective and subjective parameters closely followed by ESP that obtained similar efficiency in some studies, especially when combined with anterior palatoplasty (AP), but with a higher incidence of complications. While LP showed moderate efficiency compared with BRP or ESP, the UPPP techniques exhibited greater outcome variability among studies, with a success rate ranging from 38.71% to 59.26%, and the best results observed in a multilevel context. <i>Conclusions:</i> In our review, BRP was the most preferred, effective, and safe among all velopharyngeal techniques, closely followed by ESP. However, older described techniques also showed good results in well-selected patients. Larger-scale studies, preferably prospective, that rigorously incorporate DISE-based strict inclusion criteria might be needed to assess the efficacy of different techniques and generalize the findings.https://www.mdpi.com/1648-9144/59/6/1147obstructive sleep apneapalatopharyngeal surgerybarbed reposition pharyngoplastyexpansion sphincter pharyngoplastyuvulopalatopharyngoplasty
spellingShingle Ana Maria Vlad
Cristian Dragos Stefanescu
Iemima Stefan
Viorel Zainea
Razvan Hainarosie
Comparative Efficacy of Velopharyngeal Surgery Techniques for Obstructive Sleep Apnea: A Systematic Review
Medicina
obstructive sleep apnea
palatopharyngeal surgery
barbed reposition pharyngoplasty
expansion sphincter pharyngoplasty
uvulopalatopharyngoplasty
title Comparative Efficacy of Velopharyngeal Surgery Techniques for Obstructive Sleep Apnea: A Systematic Review
title_full Comparative Efficacy of Velopharyngeal Surgery Techniques for Obstructive Sleep Apnea: A Systematic Review
title_fullStr Comparative Efficacy of Velopharyngeal Surgery Techniques for Obstructive Sleep Apnea: A Systematic Review
title_full_unstemmed Comparative Efficacy of Velopharyngeal Surgery Techniques for Obstructive Sleep Apnea: A Systematic Review
title_short Comparative Efficacy of Velopharyngeal Surgery Techniques for Obstructive Sleep Apnea: A Systematic Review
title_sort comparative efficacy of velopharyngeal surgery techniques for obstructive sleep apnea a systematic review
topic obstructive sleep apnea
palatopharyngeal surgery
barbed reposition pharyngoplasty
expansion sphincter pharyngoplasty
uvulopalatopharyngoplasty
url https://www.mdpi.com/1648-9144/59/6/1147
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