Genetic polymorphism and natural selection of circumsporozoite surface protein in Plasmodium falciparum field isolates from Myanmar

Genetic polymorphism and natural selection of circumsporozoite surface protein in Plasmodium falciparum field isolates from Myanmar

Abstract Background Plasmodium falciparum circumsporozoite protein (PfCSP) is one of the most extensively studied malaria vaccine candidates, but the genetic polymorphism of PfCSP within and among the global P. falciparum population raises concerns regarding the efficacy of a PfCSP-based vaccine eff...

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Bibliographic Details
Main Authors: Hương Giang Lê, Jung-Mi Kang, Mya Moe, Hojong Jun, Thị Lam Thái, Jinyoung Lee, Moe Kyaw Myint, Khin Lin, Woon-Mok Sohn, Ho-Joon Shin, Tong-Soo Kim, Byoung-Kuk Na
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Malaria Journal
Subjects:
Plasmodium falciparum
Circumsporozoite protein
Genetic polymorphism
Natural selection
Myanmar
Online Access:http://link.springer.com/article/10.1186/s12936-018-2513-0

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