Gene regulatory network reconstruction using single-cell RNA sequencing of barcoded genotypes in diverse environments

Gene regulatory network reconstruction using single-cell RNA sequencing of barcoded genotypes in diverse environments

Understanding how gene expression programs are controlled requires identifying regulatory relationships between transcription factors and target genes. Gene regulatory networks are typically constructed from gene expression data acquired following genetic perturbation or environmental stimulus. Sing...

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Bibliographic Details
Main Authors: Christopher A Jackson, Dayanne M Castro, Giuseppe-Antonio Saldi, Richard Bonneau, David Gresham
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-01-01
Series:eLife
Subjects:
single cell RNA sequencing
gene regulatory networks
transcription factors
Online Access:https://elifesciences.org/articles/51254

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