MORPHOLOGICAL AND HISTOCHEMIKAL CHANGES OF LIVER IN ACETATE STOMACH ULCER AND CHRONIK INFLUENCE OF HEXACHLORCYCLOHEXAN PESTICIDE
On the background of long peroral administration of HChCH at the dose of 10 maximum permissible concentrations (MPC) in animals with an acetate ulcer its penetrations into liver increases (10-20%) with the simultaneous rise of defensive-adaptive metabolic processes in it. With an increase of the dos...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
Kamerton
2011-01-01
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| Series: | Юг России: экология, развитие |
| Subjects: |
| Summary: | On the background of long peroral administration of HChCH at the dose of 10 maximum permissible concentrations (MPC) in animals with an acetate ulcer its penetrations into liver increases (10-20%) with the simultaneous rise of defensive-adaptive metabolic processes in it. With an increase of the dose of the administrated pesticide up to 50-100 MPC the aggressive course of ulcer with an increase of the frequency of its penetration into liver (up to 100% in the dose of 100 MPC) and op-pression of the activity of all the dehydrogenases, MAO, strengthening of glycogenolysis, the drop of RNA synthesis in hepa-tocytes are noticed. Simultaneously, the raised activity of acid phosphatase, alkaline phosphatase is saved that testifies to activization of hydrolytic and fibroblastic processes of the defensive nature. |
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| ISSN: | 1992-1098 2413-0958 |