MORPHOLOGICAL AND HISTOCHEMIKAL CHANGES OF LIVER IN ACETATE STOMACH ULCER AND CHRONIK INFLUENCE OF HEXACHLORCYCLOHEXAN PESTICIDE
On the background of long peroral administration of HChCH at the dose of 10 maximum permissible concentrations (MPC) in animals with an acetate ulcer its penetrations into liver increases (10-20%) with the simultaneous rise of defensive-adaptive metabolic processes in it. With an increase of the dos...
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| Format: | Article |
| Language: | Russian |
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Kamerton
2011-01-01
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| Series: | Юг России: экология, развитие |
| Subjects: |
| _version_ | 1811203068824387584 |
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| author | M. A. Shakhnazarov A. M. Shakhnazarov M. T. Rasulov B. G. Magomedgadzhiev A. O. Medzhidov |
| author_facet | M. A. Shakhnazarov A. M. Shakhnazarov M. T. Rasulov B. G. Magomedgadzhiev A. O. Medzhidov |
| author_sort | M. A. Shakhnazarov |
| collection | DOAJ |
| description | On the background of long peroral administration of HChCH at the dose of 10 maximum permissible concentrations (MPC) in animals with an acetate ulcer its penetrations into liver increases (10-20%) with the simultaneous rise of defensive-adaptive metabolic processes in it. With an increase of the dose of the administrated pesticide up to 50-100 MPC the aggressive course of ulcer with an increase of the frequency of its penetration into liver (up to 100% in the dose of 100 MPC) and op-pression of the activity of all the dehydrogenases, MAO, strengthening of glycogenolysis, the drop of RNA synthesis in hepa-tocytes are noticed. Simultaneously, the raised activity of acid phosphatase, alkaline phosphatase is saved that testifies to activization of hydrolytic and fibroblastic processes of the defensive nature. |
| first_indexed | 2024-04-12T02:49:19Z |
| format | Article |
| id | doaj.art-2186466e3ca84c8dbcf60a2665ffaf75 |
| institution | Directory Open Access Journal |
| issn | 1992-1098 2413-0958 |
| language | Russian |
| last_indexed | 2024-04-12T02:49:19Z |
| publishDate | 2011-01-01 |
| publisher | Kamerton |
| record_format | Article |
| series | Юг России: экология, развитие |
| spelling | doaj.art-2186466e3ca84c8dbcf60a2665ffaf752022-12-22T03:51:02ZrusKamertonЮг России: экология, развитие1992-10982413-09582011-01-016311211710.18470/1992-1098-2011-3-112-117269MORPHOLOGICAL AND HISTOCHEMIKAL CHANGES OF LIVER IN ACETATE STOMACH ULCER AND CHRONIK INFLUENCE OF HEXACHLORCYCLOHEXAN PESTICIDEM. A. Shakhnazarov0A. M. Shakhnazarov1M. T. Rasulov2B. G. Magomedgadzhiev3A. O. Medzhidov4Дагестанская государственная медицинская академияДагестанская государственная медицинская академияДагестанская государственная медицинская академияДагестанская государственная медицинская академияДагестанская государственная медицинская академияOn the background of long peroral administration of HChCH at the dose of 10 maximum permissible concentrations (MPC) in animals with an acetate ulcer its penetrations into liver increases (10-20%) with the simultaneous rise of defensive-adaptive metabolic processes in it. With an increase of the dose of the administrated pesticide up to 50-100 MPC the aggressive course of ulcer with an increase of the frequency of its penetration into liver (up to 100% in the dose of 100 MPC) and op-pression of the activity of all the dehydrogenases, MAO, strengthening of glycogenolysis, the drop of RNA synthesis in hepa-tocytes are noticed. Simultaneously, the raised activity of acid phosphatase, alkaline phosphatase is saved that testifies to activization of hydrolytic and fibroblastic processes of the defensive nature.liverhexachlorcyclohexanstomach ulcerpenetrations |
| spellingShingle | M. A. Shakhnazarov A. M. Shakhnazarov M. T. Rasulov B. G. Magomedgadzhiev A. O. Medzhidov MORPHOLOGICAL AND HISTOCHEMIKAL CHANGES OF LIVER IN ACETATE STOMACH ULCER AND CHRONIK INFLUENCE OF HEXACHLORCYCLOHEXAN PESTICIDE Юг России: экология, развитие liver hexachlorcyclohexan stomach ulcer penetrations |
| title | MORPHOLOGICAL AND HISTOCHEMIKAL CHANGES OF LIVER IN ACETATE STOMACH ULCER AND CHRONIK INFLUENCE OF HEXACHLORCYCLOHEXAN PESTICIDE |
| title_full | MORPHOLOGICAL AND HISTOCHEMIKAL CHANGES OF LIVER IN ACETATE STOMACH ULCER AND CHRONIK INFLUENCE OF HEXACHLORCYCLOHEXAN PESTICIDE |
| title_fullStr | MORPHOLOGICAL AND HISTOCHEMIKAL CHANGES OF LIVER IN ACETATE STOMACH ULCER AND CHRONIK INFLUENCE OF HEXACHLORCYCLOHEXAN PESTICIDE |
| title_full_unstemmed | MORPHOLOGICAL AND HISTOCHEMIKAL CHANGES OF LIVER IN ACETATE STOMACH ULCER AND CHRONIK INFLUENCE OF HEXACHLORCYCLOHEXAN PESTICIDE |
| title_short | MORPHOLOGICAL AND HISTOCHEMIKAL CHANGES OF LIVER IN ACETATE STOMACH ULCER AND CHRONIK INFLUENCE OF HEXACHLORCYCLOHEXAN PESTICIDE |
| title_sort | morphological and histochemikal changes of liver in acetate stomach ulcer and chronik influence of hexachlorcyclohexan pesticide |
| topic | liver hexachlorcyclohexan stomach ulcer penetrations |
| work_keys_str_mv | AT mashakhnazarov morphologicalandhistochemikalchangesofliverinacetatestomachulcerandchronikinfluenceofhexachlorcyclohexanpesticide AT amshakhnazarov morphologicalandhistochemikalchangesofliverinacetatestomachulcerandchronikinfluenceofhexachlorcyclohexanpesticide AT mtrasulov morphologicalandhistochemikalchangesofliverinacetatestomachulcerandchronikinfluenceofhexachlorcyclohexanpesticide AT bgmagomedgadzhiev morphologicalandhistochemikalchangesofliverinacetatestomachulcerandchronikinfluenceofhexachlorcyclohexanpesticide AT aomedzhidov morphologicalandhistochemikalchangesofliverinacetatestomachulcerandchronikinfluenceofhexachlorcyclohexanpesticide |