TDP-43 Inhibits NF-κB Activity by Blocking p65 Nuclear Translocation.

TDP-43 Inhibits NF-κB Activity by Blocking p65 Nuclear Translocation.

TDP-43 (TAR DNA binding protein 43) is a heterogeneous nuclear ribonucleoprotein (hnRNP) that has been found to play an important role in neurodegenerative diseases. TDP-43's involvement in nuclear factor-kappaB pathways has been reported in both neurons and microglial cells. The NF-κB pathway...

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Bibliographic Details
Main Authors:	Jingyan Zhu, Max S Cynader, William Jia
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2015-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC4646651?pdf=render

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