Utility of Modeling End-Stage Liver Disease in Children with Chronic Liver Disease
Introduction: Chronic liver diseases consist of wide spectrum disorders that may be complicated by cirrhosis and therefore need to transplantation. The pediatric end-stage liver disease (PELD) score and model of end-stage liver disease (MELD) score has been used as predictors of mortality chronic li...
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| Format: | Article |
| Language: | English |
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Mashhad University of Medical Sciences
2014-01-01
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| Series: | International Journal of Pediatrics |
| Subjects: | |
| Online Access: | http://ijp.mums.ac.ir/pdf_2123_c971e53729932597c1097cf7c69289a8.html |
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| author | Hamid Reza Kianifar Sanaz Jafarzadeh Fakhari Maryam Khalesi Mohammad Ali Kiani Atefeh Ezzati Seyed Ali Jafari |
| author_facet | Hamid Reza Kianifar Sanaz Jafarzadeh Fakhari Maryam Khalesi Mohammad Ali Kiani Atefeh Ezzati Seyed Ali Jafari |
| author_sort | Hamid Reza Kianifar |
| collection | DOAJ |
| description | Introduction: Chronic liver diseases consist of wide spectrum disorders that may be complicated by cirrhosis and therefore need to transplantation. The pediatric end-stage liver disease (PELD) score and model of end-stage liver disease (MELD) score has been used as predictors of mortality chronic liver diseases listed for liver transplantation. The aim of this study is evaluation of relation between PELDMELD score and evidence of cirrhosis in children with choronic liver disease. Materials and Method: This cross-sectional study conducted on 106 patients of chronic liver disease referred to Ghaem Haspital, Mashhad University of Medical Science, Iran during 24 months period (2010-2013). PELD and MELD score were calculated for all patients. Clincal and patholoogical findings of cirrhosis were recorded. Results: Mean age of patients was 68/3 ± 41.8 months. Mean PELDMELD score was -1/59± 9/64. There was significant correlation between PELDMELD score and clinical icter, spelenomegaly, evidence of hepatopulminary syndrome, esophageal varices, evidence of cirrhosis in tissue specimences. Conclusion: PELDMELD score appear to be benefit for detection of cirrhotic children among paients with choronic liver disease. |
| first_indexed | 2024-04-11T22:29:57Z |
| format | Article |
| id | doaj.art-218fc5282cc24fb0808e3b362a04a022 |
| institution | Directory Open Access Journal |
| issn | 2345-5047 2345-5055 |
| language | English |
| last_indexed | 2024-04-11T22:29:57Z |
| publishDate | 2014-01-01 |
| publisher | Mashhad University of Medical Sciences |
| record_format | Article |
| series | International Journal of Pediatrics |
| spelling | doaj.art-218fc5282cc24fb0808e3b362a04a0222022-12-22T03:59:26ZengMashhad University of Medical SciencesInternational Journal of Pediatrics2345-50472345-50552014-01-012171742123Utility of Modeling End-Stage Liver Disease in Children with Chronic Liver DiseaseHamid Reza Kianifar0Sanaz Jafarzadeh Fakhari1Maryam Khalesi2Mohammad Ali Kiani3Atefeh Ezzati4Seyed Ali Jafari5Department of Pediatric Gastroenterology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.Department of Pediatrics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, IranDepartment of Pediatrics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, IranDepartment of Pediatric Gastroenterology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.Ghaem Hospital Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.Department of Pediatric Gastroenterology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.Introduction: Chronic liver diseases consist of wide spectrum disorders that may be complicated by cirrhosis and therefore need to transplantation. The pediatric end-stage liver disease (PELD) score and model of end-stage liver disease (MELD) score has been used as predictors of mortality chronic liver diseases listed for liver transplantation. The aim of this study is evaluation of relation between PELDMELD score and evidence of cirrhosis in children with choronic liver disease. Materials and Method: This cross-sectional study conducted on 106 patients of chronic liver disease referred to Ghaem Haspital, Mashhad University of Medical Science, Iran during 24 months period (2010-2013). PELD and MELD score were calculated for all patients. Clincal and patholoogical findings of cirrhosis were recorded. Results: Mean age of patients was 68/3 ± 41.8 months. Mean PELDMELD score was -1/59± 9/64. There was significant correlation between PELDMELD score and clinical icter, spelenomegaly, evidence of hepatopulminary syndrome, esophageal varices, evidence of cirrhosis in tissue specimences. Conclusion: PELDMELD score appear to be benefit for detection of cirrhotic children among paients with choronic liver disease.http://ijp.mums.ac.ir/pdf_2123_c971e53729932597c1097cf7c69289a8.htmlChoronic Liver DiseaseCirrhosisPELDMELD Score |
| spellingShingle | Hamid Reza Kianifar Sanaz Jafarzadeh Fakhari Maryam Khalesi Mohammad Ali Kiani Atefeh Ezzati Seyed Ali Jafari Utility of Modeling End-Stage Liver Disease in Children with Chronic Liver Disease International Journal of Pediatrics Choronic Liver Disease Cirrhosis PELDMELD Score |
| title | Utility of Modeling End-Stage Liver Disease in Children with Chronic Liver Disease |
| title_full | Utility of Modeling End-Stage Liver Disease in Children with Chronic Liver Disease |
| title_fullStr | Utility of Modeling End-Stage Liver Disease in Children with Chronic Liver Disease |
| title_full_unstemmed | Utility of Modeling End-Stage Liver Disease in Children with Chronic Liver Disease |
| title_short | Utility of Modeling End-Stage Liver Disease in Children with Chronic Liver Disease |
| title_sort | utility of modeling end stage liver disease in children with chronic liver disease |
| topic | Choronic Liver Disease Cirrhosis PELDMELD Score |
| url | http://ijp.mums.ac.ir/pdf_2123_c971e53729932597c1097cf7c69289a8.html |
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