Congenital Critical Heart Defect Screening in a Health Area of the Community of Valencia (Spain): A Prospective Observational Study
Despite the progress in the fetal echocardiographic detection of congenital critical heart defects and neonatal physical examination, a significant number of newborn infants are discharged and readmitted to the hospital in severe condition due to cardiac failure or collapse. The aim of this study wa...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2018-01-01
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| Series: | International Journal of Neonatal Screening |
| Subjects: | |
| Online Access: | http://www.mdpi.com/2409-515X/4/1/3 |
| _version_ | 1828766345784721408 |
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| author | Elena Cubells Begoña Torres Antonio Nuñez-Ramiro Manuel Sánchez-Luna Isabel Izquierdo Máximo Vento |
| author_facet | Elena Cubells Begoña Torres Antonio Nuñez-Ramiro Manuel Sánchez-Luna Isabel Izquierdo Máximo Vento |
| author_sort | Elena Cubells |
| collection | DOAJ |
| description | Despite the progress in the fetal echocardiographic detection of congenital critical heart defects and neonatal physical examination, a significant number of newborn infants are discharged and readmitted to the hospital in severe condition due to cardiac failure or collapse. The aim of this study was to assess the incidence of undetected critical congenital heart disease (CCHD) by a pulse oximetry-screening program in the maternity wards of hospitals with Perinatal Services in a specific geographic area. This is a prospective observational study performed in in the health area corresponding to the city of Valencia. Eligible infants were consecutively admitted newborn infants in the maternities of the participating hospitals with negative fetal echocardiography after normal physical examination in the delivery room. All patients were screened following a specific pulse oximetry protocol before discharge. A total of 8856 newborn infants were screened. A total of three babies presented with severe congenital cardiac malformation and two babies presented with early onset sepsis. Sensitivity was 100% and specificity was 99.97%, with a positive predictive value of 60% and negative predictive value of 100%. Pulse oximetry screening programs in the early neonatal period constitute a valuable tool to avoid inadvertent hospital discharge of severe cardiac malformations and the subsequent life-threatening complications derived. |
| first_indexed | 2024-12-11T07:04:09Z |
| format | Article |
| id | doaj.art-21900b048fd849959a972d37aee3970a |
| institution | Directory Open Access Journal |
| issn | 2409-515X |
| language | English |
| last_indexed | 2024-12-11T07:04:09Z |
| publishDate | 2018-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Neonatal Screening |
| spelling | doaj.art-21900b048fd849959a972d37aee3970a2022-12-22T01:16:33ZengMDPI AGInternational Journal of Neonatal Screening2409-515X2018-01-0141310.3390/ijns4010003ijns4010003Congenital Critical Heart Defect Screening in a Health Area of the Community of Valencia (Spain): A Prospective Observational StudyElena Cubells0Begoña Torres1Antonio Nuñez-Ramiro2Manuel Sánchez-Luna3Isabel Izquierdo4Máximo Vento5Division of Neonatology, Hospital Universitario y Politécnico La Fe, 46026 Valencia, SpainInstituto de Investigación Sanitaria La Fe, 46026 Valencia, SpainDivision of Neonatology, Hospital Universitario y Politécnico La Fe, 46026 Valencia, SpainDivision of Neonatology, Hospital Universitario Gregorio Marañón, 28007 Madrid, SpainDivision of Neonatology, Hospital Universitario y Politécnico La Fe, 46026 Valencia, SpainDivision of Neonatology, Hospital Universitario y Politécnico La Fe, 46026 Valencia, SpainDespite the progress in the fetal echocardiographic detection of congenital critical heart defects and neonatal physical examination, a significant number of newborn infants are discharged and readmitted to the hospital in severe condition due to cardiac failure or collapse. The aim of this study was to assess the incidence of undetected critical congenital heart disease (CCHD) by a pulse oximetry-screening program in the maternity wards of hospitals with Perinatal Services in a specific geographic area. This is a prospective observational study performed in in the health area corresponding to the city of Valencia. Eligible infants were consecutively admitted newborn infants in the maternities of the participating hospitals with negative fetal echocardiography after normal physical examination in the delivery room. All patients were screened following a specific pulse oximetry protocol before discharge. A total of 8856 newborn infants were screened. A total of three babies presented with severe congenital cardiac malformation and two babies presented with early onset sepsis. Sensitivity was 100% and specificity was 99.97%, with a positive predictive value of 60% and negative predictive value of 100%. Pulse oximetry screening programs in the early neonatal period constitute a valuable tool to avoid inadvertent hospital discharge of severe cardiac malformations and the subsequent life-threatening complications derived.http://www.mdpi.com/2409-515X/4/1/3oxygen saturationpulse oximetrycritical congenital heart diseasescreeningnewborn |
| spellingShingle | Elena Cubells Begoña Torres Antonio Nuñez-Ramiro Manuel Sánchez-Luna Isabel Izquierdo Máximo Vento Congenital Critical Heart Defect Screening in a Health Area of the Community of Valencia (Spain): A Prospective Observational Study International Journal of Neonatal Screening oxygen saturation pulse oximetry critical congenital heart disease screening newborn |
| title | Congenital Critical Heart Defect Screening in a Health Area of the Community of Valencia (Spain): A Prospective Observational Study |
| title_full | Congenital Critical Heart Defect Screening in a Health Area of the Community of Valencia (Spain): A Prospective Observational Study |
| title_fullStr | Congenital Critical Heart Defect Screening in a Health Area of the Community of Valencia (Spain): A Prospective Observational Study |
| title_full_unstemmed | Congenital Critical Heart Defect Screening in a Health Area of the Community of Valencia (Spain): A Prospective Observational Study |
| title_short | Congenital Critical Heart Defect Screening in a Health Area of the Community of Valencia (Spain): A Prospective Observational Study |
| title_sort | congenital critical heart defect screening in a health area of the community of valencia spain a prospective observational study |
| topic | oxygen saturation pulse oximetry critical congenital heart disease screening newborn |
| url | http://www.mdpi.com/2409-515X/4/1/3 |
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