hUMSC transplantation restores follicle development in ovary damaged mice via re-establish extracellular matrix (ECM) components

hUMSC transplantation restores follicle development in ovary damaged mice via re-establish extracellular matrix (ECM) components

Abstract Objectives Explore the therapeutic role of human umbilical mesenchymal stem cells (hUMSCs) transplantation for regeneration of ECM components and restoration of follicular development in mice. Background The extracellular matrix (ECM) is crucial to maintain ovary function and regulate folli...

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Bibliographic Details
Main Authors: Yin Shuyuan, Wang Meimei, Li Fenghua, Zhao Huishan, Chu Min, Bao Hongchu, Liu Xuemei
Format: Article
Language:English
Published: BMC 2023-08-01
Series:Journal of Ovarian Research
Subjects:
Follicular Development
Ovarian Reserve
Transcriptome sequencing
Extracellular matrix
Mesenchymal stem cells
Online Access:https://doi.org/10.1186/s13048-023-01217-y

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