Heat Shock Protein Inhibitors Show Synergistic Antibacterial Effects with Photodynamic Therapy on Caries-Related Streptococci In Vitro and In Vivo

Heat Shock Protein Inhibitors Show Synergistic Antibacterial Effects with Photodynamic Therapy on Caries-Related Streptococci In Vitro and In Vivo

ABSTRACT Caries are chronic infections in which the cariogenic biofilm plays a critical role in disease occurrence and progression. Photodynamic therapy (PDT) is a new effective treatment that is receiving wide attention in the antibacterial field, but it can lead to the upregulation of heat shock p...

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Bibliographic Details
Main Authors: Zichen Zhang, Yaoting Ji, Danfeng Liu, Shuhui Zhou, Zijun Wang, Rourong Chen, Ting Li, Boxuan Zhao, Hantao Yao, Minquan Du
Format: Article
Language:English
Published: American Society for Microbiology 2023-04-01
Series:mSphere
Subjects:
caries
chlorin e6
heat shock protein inhibitors
photodynamic therapy
Streptococcus
Online Access:https://journals.asm.org/doi/10.1128/msphere.00679-22

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