Cofilin-1 Is a Mechanosensitive Regulator of Transcription

Cofilin-1 Is a Mechanosensitive Regulator of Transcription

The mechanical properties of the extracellular environment are interrogated by cells and integrated through mechanotransduction. Many cellular processes depend on actomyosin-dependent contractility, which is influenced by the microenvironment’s stiffness. Here, we explored the influence of substrate...

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Bibliographic Details
Main Authors: Catarina Domingues, A. Margarida Geraldo, Sandra Isabel Anjo, André Matos, Cláudio Almeida, Inês Caramelo, José A. Lopes-da-Silva, Artur Paiva, João Carvalho, Ricardo Pires das Neves, Bruno Manadas, Mário Grãos
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
mechanotransduction
Cofilin-1
cytoskeleton
transcription
hUCM-MSCs
proteomics
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00678/full

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