Plasma and Urinary Metabolomic Analysis of Gout and Asymptomatic Hyperuricemia and Profiling of Potential Biomarkers: A Pilot Study

Plasma and Urinary Metabolomic Analysis of Gout and Asymptomatic Hyperuricemia and Profiling of Potential Biomarkers: A Pilot Study

Gout results from monosodium urate deposition caused by hyperuricemia, but most individuals with hyperuricemia remain asymptomatic. The pathogenesis of gout remains uncertain. To identify potential biomarkers distinguishing gout from asymptomatic hyperuricemia, we conducted a genetic analysis of ura...

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Bibliographic Details
Main Authors: Yuki Ohashi, Hiroshi Ooyama, Hideki Makinoshima, Tappei Takada, Hirotaka Matsuo, Kimiyoshi Ichida
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Biomedicines
Subjects:
gout
hyperuricemia
uric acid
ABCG2
SLC2A9
metabolomics
Online Access:https://www.mdpi.com/2227-9059/12/2/300

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