Intrathecal Pseudodelivery of Drugs in the Therapy of Neurodegenerative Diseases: Rationale, Basis and Potential Applications

Intrathecal Pseudodelivery of Drugs in the Therapy of Neurodegenerative Diseases: Rationale, Basis and Potential Applications

Intrathecal pseudodelivery of drugs is a novel route to administer medications to treat neurodegenerative diseases based on the CSF-sink therapeutic strategy by means of implantable devices. While the development of this therapy is still in the preclinical stage, it offers promising advantages over...

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Bibliographic Details
Main Authors: Menéndez-González Manuel, Bogdan-Ionel Tamba, Maxime Leclere, Mostafa Mabrouk, Thomas-Gabriel Schreiner, Romeo Ciobanu, Tomás-Zapico Cristina
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Pharmaceutics
Subjects:
drug delivery systems
intrathecal pseudodelivery
neurodegenerative diseases
intrathecal device
nanoporous membranes
Online Access:https://www.mdpi.com/1999-4923/15/3/768

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