Conjunctival impression cytology in contact lens wearers.
PURPOSE: To evaluate the cytological changes in conjunctiva following regular contact lens wear and to determine the correlation, if any, between severity of cytological alteration and symptoms related to contact lens wear. METHODS: One hundred eyes (50 normal asymptomatic subjects) who served as a...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2002-01-01
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| Series: | Indian Journal of Ophthalmology |
| Subjects: | |
| Online Access: | http://www.ijo.in/article.asp?issn=0301-4738;year=2002;volume=50;issue=4;spage=301;epage=306;aulast=Simon |
| _version_ | 1819075055376662528 |
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| author | Simon Priya Jaison Saramma Chopra Sudesh Jacob Sunitha |
| author_facet | Simon Priya Jaison Saramma Chopra Sudesh Jacob Sunitha |
| author_sort | Simon Priya |
| collection | DOAJ |
| description | PURPOSE: To evaluate the cytological changes in conjunctiva following regular contact lens wear and to determine the correlation, if any, between severity of cytological alteration and symptoms related to contact lens wear. METHODS: One hundred eyes (50 normal asymptomatic subjects) who served as a control group were studied by conjunctival impression cytology (CIC). These subjects were fitted with rigid gas permeable (RGP) or soft contact lenses and were followed up at the end of 3 and 6 months. At each follow-up visit the CIC was repeated. A filter paper with the impression specimen was stained with periodic acid schiff (PAS) and haematoxylin stain to study goblet cell loss. Papanicolaou stain was done to study squamous metaplasia. The cytological changes were graded using the system described by Natadisastra et al. RESULTS: Severity of cytological changes increased with the duration of contact lens wear (P = 0.00001). At the end of 6 months, 60% of symptomatic eyes wearing soft contact lens and RGP lens showed abnormal CIC changes. None of the asymptomatic RGP contact lens wearing eyes showed abnormal CIC changes whereas 33.4% of the asymptomatic soft contact lens wearing eyes showed abnormal CIC changes (P = 0.033). Epithelial changes occurred within 3-6 months of contact lens fitting. CONCLUSION: Severity of cytological changes increased with duration of lens wear (P = 0.00001). Prevalence and severity of cytological alteration is more in symptomatic contact lens wearers. Soft contact lens wearers although asymptomatic showed severe CIC changes. |
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| format | Article |
| id | doaj.art-2198cee4d73d4cb281c409d8a9778efd |
| institution | Directory Open Access Journal |
| issn | 0301-4738 |
| language | English |
| last_indexed | 2024-12-21T18:19:19Z |
| publishDate | 2002-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Ophthalmology |
| spelling | doaj.art-2198cee4d73d4cb281c409d8a9778efd2022-12-21T18:54:34ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47382002-01-01504301306Conjunctival impression cytology in contact lens wearers.Simon PriyaJaison SarammaChopra SudeshJacob SunithaPURPOSE: To evaluate the cytological changes in conjunctiva following regular contact lens wear and to determine the correlation, if any, between severity of cytological alteration and symptoms related to contact lens wear. METHODS: One hundred eyes (50 normal asymptomatic subjects) who served as a control group were studied by conjunctival impression cytology (CIC). These subjects were fitted with rigid gas permeable (RGP) or soft contact lenses and were followed up at the end of 3 and 6 months. At each follow-up visit the CIC was repeated. A filter paper with the impression specimen was stained with periodic acid schiff (PAS) and haematoxylin stain to study goblet cell loss. Papanicolaou stain was done to study squamous metaplasia. The cytological changes were graded using the system described by Natadisastra et al. RESULTS: Severity of cytological changes increased with the duration of contact lens wear (P = 0.00001). At the end of 6 months, 60% of symptomatic eyes wearing soft contact lens and RGP lens showed abnormal CIC changes. None of the asymptomatic RGP contact lens wearing eyes showed abnormal CIC changes whereas 33.4% of the asymptomatic soft contact lens wearing eyes showed abnormal CIC changes (P = 0.033). Epithelial changes occurred within 3-6 months of contact lens fitting. CONCLUSION: Severity of cytological changes increased with duration of lens wear (P = 0.00001). Prevalence and severity of cytological alteration is more in symptomatic contact lens wearers. Soft contact lens wearers although asymptomatic showed severe CIC changes.http://www.ijo.in/article.asp?issn=0301-4738;year=2002;volume=50;issue=4;spage=301;epage=306;aulast=SimonContact lensesimpression cytologysquamous metaplasia |
| spellingShingle | Simon Priya Jaison Saramma Chopra Sudesh Jacob Sunitha Conjunctival impression cytology in contact lens wearers. Indian Journal of Ophthalmology Contact lenses impression cytology squamous metaplasia |
| title | Conjunctival impression cytology in contact lens wearers. |
| title_full | Conjunctival impression cytology in contact lens wearers. |
| title_fullStr | Conjunctival impression cytology in contact lens wearers. |
| title_full_unstemmed | Conjunctival impression cytology in contact lens wearers. |
| title_short | Conjunctival impression cytology in contact lens wearers. |
| title_sort | conjunctival impression cytology in contact lens wearers |
| topic | Contact lenses impression cytology squamous metaplasia |
| url | http://www.ijo.in/article.asp?issn=0301-4738;year=2002;volume=50;issue=4;spage=301;epage=306;aulast=Simon |
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