The effect of lime (Citrus Aurantifola Swingle) peel extract in periodontal dressings on the number of fibroblasts in the gingival wound healing process
Background: Periodontal dressing commonly used in dentistry today does not contain compounds that can accelerate wound healing. Lime (Citrus aurantifolia Swingle) peel contains flavonoids that play a role in increasing fibroblast cells so that they can accelerate the healing process. Periodontal dre...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Universitas Airlangga
2022-06-01
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| Series: | Dental Journal |
| Subjects: | |
| Online Access: | https://e-journal.unair.ac.id/MKG/article/view/32173 |
| _version_ | 1818533674772070400 |
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| author | Malianawati Fauzia Audia Putri Dewanti |
| author_facet | Malianawati Fauzia Audia Putri Dewanti |
| author_sort | Malianawati Fauzia |
| collection | DOAJ |
| description | Background: Periodontal dressing commonly used in dentistry today does not contain compounds that can accelerate wound healing. Lime (Citrus aurantifolia Swingle) peel contains flavonoids that play a role in increasing fibroblast cells so that they can accelerate the healing process. Periodontal dressings supplemented with lime (Citrus aurantifolia Swingle) peel extract are expected to provide an alternative material that can accelerate wound healing in addition to closure. Purpose: The study aims to determine the effect of adding lime (Citrus aurantifolia Swingle) peel extract to periodontal dressings on the increase in the number of fibroblasts in the gingival healing process. Methods: The study was conducted in an experimental laboratory in vivo. The study used a post-randomised control group of 32 rabbits with lesions of the mandibular gingiva using a 2 mm diameter punch biopsy. The experimental animals were divided into 8 groups, namely the control group, which was treated with periodontal dressings without the addition of lime (Citrus aurantifolia Swingle) peel extract, and the treatment group, which was treated with periodontal dressings with the addition of the extract. Histological observations of the tissues were performed with HE staining to count the number of fibroblasts. Results: Statistical test results showed that there was a significant difference in the number of fibroblasts between the control group and the treatment group on day 3 and day 5 (ANOVA, p <0.05). Conclusion: Adding extra lime (Citrus aurantifolia Swingle) peel to the periodontal dressing increases the number of fibroblast cells after gum injury. |
| first_indexed | 2024-12-11T18:01:51Z |
| format | Article |
| id | doaj.art-219d80dfeb6c44c99bd84056bec7db6b |
| institution | Directory Open Access Journal |
| issn | 1978-3728 2442-9740 |
| language | English |
| last_indexed | 2024-12-11T18:01:51Z |
| publishDate | 2022-06-01 |
| publisher | Universitas Airlangga |
| record_format | Article |
| series | Dental Journal |
| spelling | doaj.art-219d80dfeb6c44c99bd84056bec7db6b2022-12-22T00:55:52ZengUniversitas AirlanggaDental Journal1978-37282442-97402022-06-01552818710.20473/j.djmkg.v55.i2.p81-8726379The effect of lime (Citrus Aurantifola Swingle) peel extract in periodontal dressings on the number of fibroblasts in the gingival wound healing processMalianawati Fauzia0Audia Putri Dewanti1Faculty of Dentistry, Universitas Brawijaya, Malang, IndonesiaFaculty of Dentistry, Universitas Brawijaya, Malang, IndonesiaBackground: Periodontal dressing commonly used in dentistry today does not contain compounds that can accelerate wound healing. Lime (Citrus aurantifolia Swingle) peel contains flavonoids that play a role in increasing fibroblast cells so that they can accelerate the healing process. Periodontal dressings supplemented with lime (Citrus aurantifolia Swingle) peel extract are expected to provide an alternative material that can accelerate wound healing in addition to closure. Purpose: The study aims to determine the effect of adding lime (Citrus aurantifolia Swingle) peel extract to periodontal dressings on the increase in the number of fibroblasts in the gingival healing process. Methods: The study was conducted in an experimental laboratory in vivo. The study used a post-randomised control group of 32 rabbits with lesions of the mandibular gingiva using a 2 mm diameter punch biopsy. The experimental animals were divided into 8 groups, namely the control group, which was treated with periodontal dressings without the addition of lime (Citrus aurantifolia Swingle) peel extract, and the treatment group, which was treated with periodontal dressings with the addition of the extract. Histological observations of the tissues were performed with HE staining to count the number of fibroblasts. Results: Statistical test results showed that there was a significant difference in the number of fibroblasts between the control group and the treatment group on day 3 and day 5 (ANOVA, p <0.05). Conclusion: Adding extra lime (Citrus aurantifolia Swingle) peel to the periodontal dressing increases the number of fibroblast cells after gum injury.https://e-journal.unair.ac.id/MKG/article/view/32173fibroblastslime (citrus aurantifolia swingle) peel extractperiodontal dressingwound healing |
| spellingShingle | Malianawati Fauzia Audia Putri Dewanti The effect of lime (Citrus Aurantifola Swingle) peel extract in periodontal dressings on the number of fibroblasts in the gingival wound healing process Dental Journal fibroblasts lime (citrus aurantifolia swingle) peel extract periodontal dressing wound healing |
| title | The effect of lime (Citrus Aurantifola Swingle) peel extract in periodontal dressings on the number of fibroblasts in the gingival wound healing process |
| title_full | The effect of lime (Citrus Aurantifola Swingle) peel extract in periodontal dressings on the number of fibroblasts in the gingival wound healing process |
| title_fullStr | The effect of lime (Citrus Aurantifola Swingle) peel extract in periodontal dressings on the number of fibroblasts in the gingival wound healing process |
| title_full_unstemmed | The effect of lime (Citrus Aurantifola Swingle) peel extract in periodontal dressings on the number of fibroblasts in the gingival wound healing process |
| title_short | The effect of lime (Citrus Aurantifola Swingle) peel extract in periodontal dressings on the number of fibroblasts in the gingival wound healing process |
| title_sort | effect of lime citrus aurantifola swingle peel extract in periodontal dressings on the number of fibroblasts in the gingival wound healing process |
| topic | fibroblasts lime (citrus aurantifolia swingle) peel extract periodontal dressing wound healing |
| url | https://e-journal.unair.ac.id/MKG/article/view/32173 |
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