Patulin-producing mold, toxicological, biosynthesis, and molecular detection of patulin

Mycotoxin is one of the food safety problems that raise concern because of its negative health impact and significant economic losses. Patulin is the most common mycotoxin found in fruits and its products like apple, orange, grape, pear, etc. There are 167 species reported to produce patulin; Penici...

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Main Authors: Ratih Paramastuti, Winiati Pudji Rahayu, Siti Nurjanah
Format: Article
Language:English
Published: Universitas Brawijaya, Fakultas Teknologi Pertanian 2021-12-01
Series:Advances in Food Science, Sustainable Agriculture, and Agroindustrial Engineering
Subjects:
Online Access:https://afssaae.ub.ac.id/index.php/afssaae/article/view/127/96
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author Ratih Paramastuti
Winiati Pudji Rahayu
Siti Nurjanah
author_facet Ratih Paramastuti
Winiati Pudji Rahayu
Siti Nurjanah
author_sort Ratih Paramastuti
collection DOAJ
description Mycotoxin is one of the food safety problems that raise concern because of its negative health impact and significant economic losses. Patulin is the most common mycotoxin found in fruits and its products like apple, orange, grape, pear, etc. There are 167 species reported to produce patulin; Penicillium expansum is the major patulin producer among those fungi species. Patulin is not classifiable as to its carcinogenicity to humans, but some studies showed the toxicities of patulin. Patulin has a broad spectrum of toxicity such as acute toxicity, sub-acute toxicity, genotoxicity, embryotoxicity and teratogenicity, carcinogenicity, and immunotoxicity. There are several ways to detect mycotoxins, such as HPLC, TLC, ELISA, and PCR. The popular way to detect mycotoxin molecularly is PCR because of its sensitivity and specificity. To detect patulin molecularly require proper selection of target gene. Therefore, the biosynthesis of patulin, its influencing gene, and its underlying factor needs to be understood.
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spelling doaj.art-219e292b08ab4ae3b297fc5d49d8bcad2023-06-23T12:53:29ZengUniversitas Brawijaya, Fakultas Teknologi PertanianAdvances in Food Science, Sustainable Agriculture, and Agroindustrial Engineering2622-59212021-12-01429310910.21776/ub.afssaae.2021.004.02.3Patulin-producing mold, toxicological, biosynthesis, and molecular detection of patulinRatih Paramastuti0Winiati Pudji Rahayu1Siti Nurjanah2IPB UnivesityIPB UnivesityIPB UnivesityMycotoxin is one of the food safety problems that raise concern because of its negative health impact and significant economic losses. Patulin is the most common mycotoxin found in fruits and its products like apple, orange, grape, pear, etc. There are 167 species reported to produce patulin; Penicillium expansum is the major patulin producer among those fungi species. Patulin is not classifiable as to its carcinogenicity to humans, but some studies showed the toxicities of patulin. Patulin has a broad spectrum of toxicity such as acute toxicity, sub-acute toxicity, genotoxicity, embryotoxicity and teratogenicity, carcinogenicity, and immunotoxicity. There are several ways to detect mycotoxins, such as HPLC, TLC, ELISA, and PCR. The popular way to detect mycotoxin molecularly is PCR because of its sensitivity and specificity. To detect patulin molecularly require proper selection of target gene. Therefore, the biosynthesis of patulin, its influencing gene, and its underlying factor needs to be understood.https://afssaae.ub.ac.id/index.php/afssaae/article/view/127/96biosynthesismolecular detectionpatulintoxicological
spellingShingle Ratih Paramastuti
Winiati Pudji Rahayu
Siti Nurjanah
Patulin-producing mold, toxicological, biosynthesis, and molecular detection of patulin
Advances in Food Science, Sustainable Agriculture, and Agroindustrial Engineering
biosynthesis
molecular detection
patulin
toxicological
title Patulin-producing mold, toxicological, biosynthesis, and molecular detection of patulin
title_full Patulin-producing mold, toxicological, biosynthesis, and molecular detection of patulin
title_fullStr Patulin-producing mold, toxicological, biosynthesis, and molecular detection of patulin
title_full_unstemmed Patulin-producing mold, toxicological, biosynthesis, and molecular detection of patulin
title_short Patulin-producing mold, toxicological, biosynthesis, and molecular detection of patulin
title_sort patulin producing mold toxicological biosynthesis and molecular detection of patulin
topic biosynthesis
molecular detection
patulin
toxicological
url https://afssaae.ub.ac.id/index.php/afssaae/article/view/127/96
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AT winiatipudjirahayu patulinproducingmoldtoxicologicalbiosynthesisandmoleculardetectionofpatulin
AT sitinurjanah patulinproducingmoldtoxicologicalbiosynthesisandmoleculardetectionofpatulin