Body Mass Index Did Not Affect the Risk of Revision 3-9 Years After Total Knee Replacement Surgery

Background: There are conflicting reports in the literature regarding the risk of revision after primary total knee replacement (TKR) in obese patients. The purpose of this study was to investigate if body mass index (BMI) influences the risk of revision 3-9 years after primary TKR. Methods: All pat...

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Main Authors: Jan Rune Mikaelsen, MD, Rune Bruhn Jakobsen, MD, PhD, Jan Harald Røtterud, MD, PhD, Per-Henrik Randsborg, MD, PhD
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:Arthroplasty Today
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S235234412400061X
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author Jan Rune Mikaelsen, MD
Rune Bruhn Jakobsen, MD, PhD
Jan Harald Røtterud, MD, PhD
Per-Henrik Randsborg, MD, PhD
author_facet Jan Rune Mikaelsen, MD
Rune Bruhn Jakobsen, MD, PhD
Jan Harald Røtterud, MD, PhD
Per-Henrik Randsborg, MD, PhD
author_sort Jan Rune Mikaelsen, MD
collection DOAJ
description Background: There are conflicting reports in the literature regarding the risk of revision after primary total knee replacement (TKR) in obese patients. The purpose of this study was to investigate if body mass index (BMI) influences the risk of revision 3-9 years after primary TKR. Methods: All patients undergoing a primary TKR in our institution from 2014 to 2018 were included in a retrospective study. The effect of BMI on all-cause revision was estimated in a logistic regression analysis. A directed acyclic graph was created to identify variables affecting the primary endpoint (revision). According to the directed acyclic graph, adjustment was only needed for age and smoking. However, we also included variables thought to influence the revision risk based on clinical experience and previous research. The final logistic regression analysis was therefore adjusted for age, sex, smoking status, diabetes mellitus and the American Society of Anesthesiologists classification. Results: One thousand fifty-nine primary TKR patients with a mean age of 68.1 (standard deviation 9.4) years were included. There were 609 (57.5%) women, and the median follow-up time was 5.6 (range 3.0-9.0) years. There were 41 (3.9%) revisions. BMI did not affect the risk of revision when adjusted for relevant covariates in a multivariate logistic regression analysis (odds ratio 0.99, 95% confidence interval 0.93-1.05, P = .6). Conclusions: BMI did not influence the risk of revision rate 3-9 years after TKR.
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spelling doaj.art-21a1c69cb8364f99b520c858bd0939ef2024-04-17T04:49:18ZengElsevierArthroplasty Today2352-34412024-06-0127101376Body Mass Index Did Not Affect the Risk of Revision 3-9 Years After Total Knee Replacement SurgeryJan Rune Mikaelsen, MD0Rune Bruhn Jakobsen, MD, PhD1Jan Harald Røtterud, MD, PhD2Per-Henrik Randsborg, MD, PhD3Department of Orthopaedic Surgery, Akershus University Hospital, Lørenskog, Norway; Faculty of Medicine, Institute of Clinical Medicine, Campus Ahus, University of Oslo, Lørenskog, Norway; Corresponding author. Department of Orthopaedic Surgery, Akershus University Hospital, Postboks 1000, 1478 Lørenskog, Norway. Tel.: +1 479 849 3257.Department of Orthopaedic Surgery, Akershus University Hospital, Lørenskog, Norway; Faculty of Medicine, Institute of Health and Society, University of Oslo, Oslo, NorwayDepartment of Orthopaedic Surgery, Akershus University Hospital, Lørenskog, NorwayDepartment of Orthopaedic Surgery, Akershus University Hospital, Lørenskog, Norway; Faculty of Medicine, Institute of Clinical Medicine, Campus Ahus, University of Oslo, Lørenskog, NorwayBackground: There are conflicting reports in the literature regarding the risk of revision after primary total knee replacement (TKR) in obese patients. The purpose of this study was to investigate if body mass index (BMI) influences the risk of revision 3-9 years after primary TKR. Methods: All patients undergoing a primary TKR in our institution from 2014 to 2018 were included in a retrospective study. The effect of BMI on all-cause revision was estimated in a logistic regression analysis. A directed acyclic graph was created to identify variables affecting the primary endpoint (revision). According to the directed acyclic graph, adjustment was only needed for age and smoking. However, we also included variables thought to influence the revision risk based on clinical experience and previous research. The final logistic regression analysis was therefore adjusted for age, sex, smoking status, diabetes mellitus and the American Society of Anesthesiologists classification. Results: One thousand fifty-nine primary TKR patients with a mean age of 68.1 (standard deviation 9.4) years were included. There were 609 (57.5%) women, and the median follow-up time was 5.6 (range 3.0-9.0) years. There were 41 (3.9%) revisions. BMI did not affect the risk of revision when adjusted for relevant covariates in a multivariate logistic regression analysis (odds ratio 0.99, 95% confidence interval 0.93-1.05, P = .6). Conclusions: BMI did not influence the risk of revision rate 3-9 years after TKR.http://www.sciencedirect.com/science/article/pii/S235234412400061XTotal knee replacementObesityBMIRisk of revision
spellingShingle Jan Rune Mikaelsen, MD
Rune Bruhn Jakobsen, MD, PhD
Jan Harald Røtterud, MD, PhD
Per-Henrik Randsborg, MD, PhD
Body Mass Index Did Not Affect the Risk of Revision 3-9 Years After Total Knee Replacement Surgery
Arthroplasty Today
Total knee replacement
Obesity
BMI
Risk of revision
title Body Mass Index Did Not Affect the Risk of Revision 3-9 Years After Total Knee Replacement Surgery
title_full Body Mass Index Did Not Affect the Risk of Revision 3-9 Years After Total Knee Replacement Surgery
title_fullStr Body Mass Index Did Not Affect the Risk of Revision 3-9 Years After Total Knee Replacement Surgery
title_full_unstemmed Body Mass Index Did Not Affect the Risk of Revision 3-9 Years After Total Knee Replacement Surgery
title_short Body Mass Index Did Not Affect the Risk of Revision 3-9 Years After Total Knee Replacement Surgery
title_sort body mass index did not affect the risk of revision 3 9 years after total knee replacement surgery
topic Total knee replacement
Obesity
BMI
Risk of revision
url http://www.sciencedirect.com/science/article/pii/S235234412400061X
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