Detection of HIV-1 infections in blood donors during the pre-seroconversion window period in São Paulo, Brazil
Abstract By decreasing the pre-seroconversion window period, nucleic acid testing (NAT) has improved the safety of blood products and reduced the risk of transfusion-transmitted infections. Between 2011 and 2017, NAT determinations for approximately 898,202 donations were performed at Fundação Pró-S...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Medicina Tropical (SBMT)
2019-05-01
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| Series: | Revista da Sociedade Brasileira de Medicina Tropical |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822019000100715&lng=en&tlng=en |
| _version_ | 1811340403827277824 |
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| author | Nanci Alves Salles Anna Shoko Nishiya Suzete Cleusa Ferreira Vanderson Geraldo Rocha Alfredo Mendrone-Junior |
| author_facet | Nanci Alves Salles Anna Shoko Nishiya Suzete Cleusa Ferreira Vanderson Geraldo Rocha Alfredo Mendrone-Junior |
| author_sort | Nanci Alves Salles |
| collection | DOAJ |
| description | Abstract By decreasing the pre-seroconversion window period, nucleic acid testing (NAT) has improved the safety of blood products and reduced the risk of transfusion-transmitted infections. Between 2011 and 2017, NAT determinations for approximately 898,202 donations were performed at Fundação Pró-Sangue/Hemocentro de São Paulo (FPS-HSP). Three seronegative HIV-viremic donations were detected. The NAT yield rate per million donations was 3.34 for HIV, and the acute HIV-1 infections detected are described, followed by a brief review of the situation in Brazil. |
| first_indexed | 2024-04-13T18:41:28Z |
| format | Article |
| id | doaj.art-21a3a9bab44f4730a1b710715a180710 |
| institution | Directory Open Access Journal |
| issn | 1678-9849 |
| language | English |
| last_indexed | 2024-04-13T18:41:28Z |
| publishDate | 2019-05-01 |
| publisher | Sociedade Brasileira de Medicina Tropical (SBMT) |
| record_format | Article |
| series | Revista da Sociedade Brasileira de Medicina Tropical |
| spelling | doaj.art-21a3a9bab44f4730a1b710715a1807102022-12-22T02:34:42ZengSociedade Brasileira de Medicina Tropical (SBMT)Revista da Sociedade Brasileira de Medicina Tropical1678-98492019-05-0152010.1590/0037-8682-0432-2018S0037-86822019000100715Detection of HIV-1 infections in blood donors during the pre-seroconversion window period in São Paulo, BrazilNanci Alves SallesAnna Shoko NishiyaSuzete Cleusa FerreiraVanderson Geraldo RochaAlfredo Mendrone-JuniorAbstract By decreasing the pre-seroconversion window period, nucleic acid testing (NAT) has improved the safety of blood products and reduced the risk of transfusion-transmitted infections. Between 2011 and 2017, NAT determinations for approximately 898,202 donations were performed at Fundação Pró-Sangue/Hemocentro de São Paulo (FPS-HSP). Three seronegative HIV-viremic donations were detected. The NAT yield rate per million donations was 3.34 for HIV, and the acute HIV-1 infections detected are described, followed by a brief review of the situation in Brazil.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822019000100715&lng=en&tlng=enHIVNAT-HIVWindow period |
| spellingShingle | Nanci Alves Salles Anna Shoko Nishiya Suzete Cleusa Ferreira Vanderson Geraldo Rocha Alfredo Mendrone-Junior Detection of HIV-1 infections in blood donors during the pre-seroconversion window period in São Paulo, Brazil Revista da Sociedade Brasileira de Medicina Tropical HIV NAT-HIV Window period |
| title | Detection of HIV-1 infections in blood donors during the pre-seroconversion window period in São Paulo, Brazil |
| title_full | Detection of HIV-1 infections in blood donors during the pre-seroconversion window period in São Paulo, Brazil |
| title_fullStr | Detection of HIV-1 infections in blood donors during the pre-seroconversion window period in São Paulo, Brazil |
| title_full_unstemmed | Detection of HIV-1 infections in blood donors during the pre-seroconversion window period in São Paulo, Brazil |
| title_short | Detection of HIV-1 infections in blood donors during the pre-seroconversion window period in São Paulo, Brazil |
| title_sort | detection of hiv 1 infections in blood donors during the pre seroconversion window period in sao paulo brazil |
| topic | HIV NAT-HIV Window period |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822019000100715&lng=en&tlng=en |
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