Subthalamic deep brain stimulation reduces pathological information transmission to the thalamus in a rat model of parkinsonism

Subthalamic deep brain stimulation reduces pathological information transmission to the thalamus in a rat model of parkinsonism

The degeneration of dopaminergic neurons in the substantia nigra pars compacta leads to parkinsonian motor symptoms via changes in electrophysiological activity throughout the basal ganglia. High-frequency deep brain stimulation (DBS) partially treats these symptoms, but the mechanisms are unclear....

Full description

Bibliographic Details
Main Authors:	Collin James Anderson, Daylan T Sheppard, Rachel eHuynh, Daria Nesterovich Anderson, Christian A Polar, Alan D Dorval
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2015-07-01
Series:	Frontiers in Neural Circuits
Subjects:	Deep Brain Stimulation Parkinson Disease Thalamic Nuclei 6-hydroxydopamine substantia nigra pars reticulata neural information
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fncir.2015.00031/full

Similar Items

Cerebellar and basal ganglia inputs define three main nuclei in the mouse ventral motor thalamus
by: Carmen Alonso-Martínez, et al.
Published: (2023-08-01)

Corrigendum: Cerebellar and basal ganglia inputs define three main nuclei in the mouse ventral motor thalamus
by: Carmen Alonso-Martínez, et al.
Published: (2023-11-01)

Lesion of the subthalamic nucleus reverses motor deficits but not death of nigrostriatal dopaminergic neurons in a rat 6-hydroxydopamine-lesion model of Parkinson's disease
by: V. Rizelio, et al.
Published: (2010-01-01)

Lead-Induced Atypical Parkinsonism in Rats: Behavioral, Electrophysiological, and Neurochemical Evidence for a Role of Noradrenaline Depletion
by: Mariam Sabbar, et al.
Published: (2018-03-01)

Persistent synaptic inhibition of the subthalamic nucleus by high frequency stimulation
by: Leon A. Steiner, et al.
Published: (2022-09-01)

The dosage of curcumin to alleviate movement symptoms in a 6-hydroxydopamine-induced Parkinson's disease rat model
by: Xiaoyu Liu, et al.
Published: (2023-06-01)

Novelty encoding by the output neurons of the basal ganglia
by: Mati Joshua, et al.
Published: (2010-01-01)

Subthalamic nucleus stimulation attenuates motor seizures via modulating the nigral orexin pathway
by: Tao Xue, et al.
Published: (2023-05-01)

Altered basal ganglia output during self-restraint
by: Bon-Mi Gu, et al.
Published: (2022-11-01)

A Network-Level Stochastic Model for Pacemaker GABAergic Neurons in Substantia Nigra Pars Reticulata
by: Karine Guimarães, et al.
Published: (2023-09-01)

Basal ganglia output reflects internally-specified movements
by: Mario J Lintz, et al.
Published: (2016-07-01)

High-Frequency Deep Brain Stimulation of the Substantia Nigra Pars Reticulata Facilitates Extinction and Prevents Reinstatement of Methamphetamine-Induced Conditioned Place Preference
by: Libo Zhang, et al.
Published: (2021-06-01)

Gait Analysis for Early Detection of Motor Symptoms in the 6-OHDA Rat Model of Parkinson's Disease
by: Jordi Boix, et al.
Published: (2018-03-01)

Reduced paired pulse depression in the basal ganglia of dystonia patients
by: I.A. Prescott, et al.
Published: (2013-03-01)

A Computational Model of Loss of Dopaminergic Cells in Parkinson's Disease Due to Glutamate-Induced Excitotoxicity
by: Vignayanandam Ravindernath Muddapu, et al.
Published: (2019-02-01)

Neurons gating behavior—developmental, molecular and functional features of neurons in the Substantia Nigra pars reticulata
by: Juha Partanen, et al.
Published: (2022-09-01)

Serotonergic neurons mediate ectopic release of dopamine induced by l-DOPA in a rat model of Parkinson's disease
by: Sylvia Navailles, et al.
Published: (2010-04-01)

Intraoperative Microelectrode Recordings in Substantia Nigra Pars Reticulata in Anesthetized Rats
by: Hanyan Li, et al.
Published: (2020-04-01)

Increased Serum Lithium Level due to Mild to Moderate damage to Dopaminergic Neurons of the Substantia Nigra, Evidence from Animal Model of Parkinson’s Disease induced by 6-Hydoxydopamine
by: Mohammad Hossein Esmaeili, et al.
Published: (2022-12-01)

Motor cortico-nigral and cortico-entopeduncular information transmission and its modulation by buspirone in control and after dopaminergic denervation
by: Sergio Vegas-Suárez, et al.
Published: (2022-08-01)

Severity of Dyskinesia and D3R Signaling Changes Induced by L-DOPA Treatment of Hemiparkinsonian Rats Are Features Inherent to the Treated Subjects
by: Sacnité Albarrán-Bravo, et al.
Published: (2019-09-01)

Direct and indirect pathway neurons in ventrolateral striatum differentially regulate licking movement and nigral responses
by: Zhaorong Chen, et al.
Published: (2021-10-01)

Dopaminergic denervation impairs cortical motor and associative/limbic information processing through the basal ganglia and its modulation by the CB1 receptor
by: Mario Antonazzo, et al.
Published: (2021-01-01)

Deep Brain Stimulation in Drug Addiction Treatment: Research Progress and Perspective
by: Rui Chang, et al.
Published: (2022-04-01)

Oxidative Stress and Genetics in the Pathogenesis of Parkinson's Disease
by: Yi Zhang, et al.
Published: (2000-08-01)

Transcranial sonography findings related to depression in parkinsonian disorders: cross-sectional study in 126 patients
by: Angela E.P. Bouwmans, et al.
Published: (2016-05-01)

Cervical dystonia: a disorder of the midbrain network for covert attentional orienting.
by: Michael eHutchinson, et al.
Published: (2014-04-01)

A Multi-Scale Computational Model of Levodopa-Induced Toxicity in Parkinson's Disease
by: Vignayanandam Ravindernath-Jayashree Muddapu, et al.
Published: (2022-04-01)

Height and nigral neuron density in Parkinson’s disease
by: Laura Saari, et al.
Published: (2022-07-01)

Habitual behavior and dopamine cell vulnerability in Parkinson disease
by: Ledia eF. Hernandez, et al.
Published: (2015-11-01)

Recent Updates in Redox Regulation and Free Radical Scavenging Effects by Herbal Products in Experimental Models of Parkinson’s Disease
by: Soon-Min Hong, et al.
Published: (2012-09-01)

Toll-like Receptor 4 Is Upregulated in Parkinson’s Disease Patients and Co-Localizes with pSer129αSyn: A Possible Link with the Pathology
by: Carmela Conte, et al.
Published: (2023-05-01)

EL NÚCLEO PEDUNCULOPONTINO Y SU RELACIÓN CON LA FISIOPATOLOGÍA DE LA ENFERMEDAD DE PARKINSON
by: LISETTE BLANCO LEZCANO, et al.
Published: (2012-09-01)

The Construction and Validation of a Novel Ferroptosis-Related Gene Signature in Parkinson’s Disease
by: Tingting Liu, et al.
Published: (2023-12-01)

Deep brain stimulation in a patient with progressive myoclonic epilepsy and ataxia due to potassium channel mutation (MEAK). A case report and review of the literature
by: Michał Sobstyl, et al.
Published: (2023-01-01)

Kappa Opioid Receptors Reduce Serotonin Uptake and Escitalopram Efficacy in the Mouse Substantia Nigra Pars Reticulata
by: Alyssa M. West, et al.
Published: (2023-01-01)

Pedunculopontine neurons are involved in network changes in the kindling model of temporal lobe epilepsy
by: Marc W. Nolte, et al.
Published: (2006-07-01)

Combined Stimulation of the Substantia Nigra and the Subthalamic Nucleus for the Treatment of Refractory Gait Disturbances in Parkinson’s Disease: A Preliminary Study
by: Marta Villadóniga, et al.
Published: (2022-04-01)

Proteomic Characterization of Synaptosomes from Human Substantia Nigra Indicates Altered Mitochondrial Translation in Parkinson’s Disease
by: Sarah Plum, et al.
Published: (2020-12-01)

Co-Expression of Nogo-A in Dopaminergic Neurons of the Human Substantia Nigra Pars Compacta Is Reduced in Parkinson’s Disease
by: Gian-Carlo Eyer, et al.
Published: (2021-11-01)