Real-time visualization and quantitation of vascular permeability in vivo: implications for drug delivery.
The leaky, heterogeneous vasculature of human tumors prevents the even distribution of systemic drugs within cancer tissues. However, techniques for studying vascular delivery systems in vivo often require complex mammalian models and time-consuming, surgical protocols. The developing chicken embryo...
Main Authors: | Desmond B S Pink, Wendy Schulte, Missag H Parseghian, Andries Zijlstra, John D Lewis |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3315578?pdf=render |
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