RBCK1 is an endogenous inhibitor for triple negative breast cancer via hippo/YAP axis
Abstract Background Triple negative breast cancer (TNBC) is one of the most lethal breast cancer subtypes. Due to a lack of effective therapeutic targets, chemotherapy is still the main medical treatment for TNBC patients. Thus, it is important and necessary to find new therapeutic targets for TNBC....
Main Authors: | Zhongbo Li, Peng Su, Yinlu Ding, Honglei Gao, Huijie Yang, Xin Li, Xiao Yang, Yan Xia, Chenmiao Zhang, Mingxi Fu, Dehai Wang, Ye Zhang, Shu Zhuo, Jian Zhu, Ting Zhuang |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2022-10-01
|
Series: | Cell Communication and Signaling |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12964-022-00963-8 |
Similar Items
-
RNF181 modulates Hippo signaling and triple negative breast cancer progression
by: Rui Zhou, et al.
Published: (2020-07-01) -
Expanding the phenotype of RBCK1-associated polyglucosan body myopathy type 1
by: Manuel Pühringer, et al.
Published: (2024-03-01) -
The E3 ubiquitin ligase RBCK1: Implications in the tumor immune microenvironment and antiangiogenic therapy of glioma
by: Jing Guo, et al.
Published: (2023-01-01) -
Identification of Key Genes and Pathways in RBCK1 Deficient patients by Gene Expression Profiling
by: Khyber Shinwari, et al.
Published: (2021-07-01) -
Role of Hippo/YAP signaling in irradiation-induced glioma cell apoptosis
by: Xu X, et al.
Published: (2019-08-01)