Perinatal mesenchymal stromal cells of the human decidua restore continence in rats with stress urinary incontinence induced by simulated birth trauma and regulate senescence of fibroblasts from women with stress urinary incontinence

Perinatal mesenchymal stromal cells of the human decidua restore continence in rats with stress urinary incontinence induced by simulated birth trauma and regulate senescence of fibroblasts from women with stress urinary incontinence

Stress urinary incontinence (SUI) is a condition that causes the involuntary loss of urine when making small efforts, which seriously affects daily life of people who suffer from it. Women are more affected by this form of incontinence than men, since parity is the main risk factor. Weakening of the...

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Bibliographic Details
Main Authors: Paz De La Torre, María Jesús Pérez-Lorenzo, Álvaro Alcázar-Garrido, Jennifer Collado, Mario Martínez-López, Laura Forcén, Ana R. Masero-Casasola, Alicia García, Mª Carmen Gutiérrez-Vélez, José Medina-Polo, Eloy Muñoz, Ana I. Flores
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
stress urinary incontinence
vaginal distention
perinatal mesenchymal stromal cells
myofibroblast
senescence
extracellular matrix remodeling
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.1033080/full

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https://www.frontiersin.org/articles/10.3389/fcell.2022.1033080/full

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