Combination types between graphene oxide and substrate affect the antibacterial activity
Duo to their superior physicochemical properties, graphene and its derivatives (GDs), such as graphene oxide (GO) and reduced graphene oxide (rGO), have attracted extensive research interests around the world. In recent years, antibacterial activities of GDs have aroused wide concern and substantial...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
KeAi Communications Co., Ltd.
2018-09-01
|
| Series: | Bioactive Materials |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2452199X18300136 |
| _version_ | 1797203686877822976 |
|---|---|
| author | Jiajun Qiu Lu Liu Hongqin Zhu Xuanyong Liu |
| author_facet | Jiajun Qiu Lu Liu Hongqin Zhu Xuanyong Liu |
| author_sort | Jiajun Qiu |
| collection | DOAJ |
| description | Duo to their superior physicochemical properties, graphene and its derivatives (GDs), such as graphene oxide (GO) and reduced graphene oxide (rGO), have attracted extensive research interests around the world. In recent years, antibacterial activities of GDs have aroused wide concern and substantial works have been done. However, the underlying antibacterial mechanisms still remain controversial. Antibacterial activities of GDs vary with various factors, such as size, number of layers, oxygen-containing groups, and experimental surroundings. We assume that combination types between graphene oxide and substrate may affect the antibacterial activity. Therefore, in this work, GO was fixed on the titanium surface with three kinds of combination types including drop with gravitational effects (GO-D), electrostatic interaction (GO-APS) and electrophoretic deposition (GO-EPD), and the antibacterial activities in vitro were systematically investigated. Results showed that combination types affected the ability of GO for preventing Staphylococcus aureus (S. aureus) from gathering, sharpness of wrinkles or edges and reactive oxygen spices (ROS) levels. Once S. aureus are in the form of separation without aggregation, GO can effectively interact with them and kill them with sharp wrinkles or edges and high ROS levels. GO-EPD could effectively prevent S. aureus from gathering, own sharp wrinkles or edges and could generate higher ROS levels. As a result, GO-EPD exhibited optimal antibacterial activity against S. aureus, followed by GO-APS and GO-D. Keywords: Graphene oxide, Antibacterial, Titanium, Combination type, S. aureus |
| first_indexed | 2024-04-24T08:23:17Z |
| format | Article |
| id | doaj.art-21afc06e85d14bd0a00ed700bf00b18a |
| institution | Directory Open Access Journal |
| issn | 2452-199X |
| language | English |
| last_indexed | 2024-04-24T08:23:17Z |
| publishDate | 2018-09-01 |
| publisher | KeAi Communications Co., Ltd. |
| record_format | Article |
| series | Bioactive Materials |
| spelling | doaj.art-21afc06e85d14bd0a00ed700bf00b18a2024-04-16T23:28:20ZengKeAi Communications Co., Ltd.Bioactive Materials2452-199X2018-09-0133341346Combination types between graphene oxide and substrate affect the antibacterial activityJiajun Qiu0Lu Liu1Hongqin Zhu2Xuanyong Liu3State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai, 200050, China; University of Chinese Academy of Sciences, Beijing, 100049, ChinaState Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai, 200050, China; Shanghai Normal University, Shanghai, 200234, ChinaState Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai, 200050, ChinaState Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai, 200050, China; Corresponding author.Duo to their superior physicochemical properties, graphene and its derivatives (GDs), such as graphene oxide (GO) and reduced graphene oxide (rGO), have attracted extensive research interests around the world. In recent years, antibacterial activities of GDs have aroused wide concern and substantial works have been done. However, the underlying antibacterial mechanisms still remain controversial. Antibacterial activities of GDs vary with various factors, such as size, number of layers, oxygen-containing groups, and experimental surroundings. We assume that combination types between graphene oxide and substrate may affect the antibacterial activity. Therefore, in this work, GO was fixed on the titanium surface with three kinds of combination types including drop with gravitational effects (GO-D), electrostatic interaction (GO-APS) and electrophoretic deposition (GO-EPD), and the antibacterial activities in vitro were systematically investigated. Results showed that combination types affected the ability of GO for preventing Staphylococcus aureus (S. aureus) from gathering, sharpness of wrinkles or edges and reactive oxygen spices (ROS) levels. Once S. aureus are in the form of separation without aggregation, GO can effectively interact with them and kill them with sharp wrinkles or edges and high ROS levels. GO-EPD could effectively prevent S. aureus from gathering, own sharp wrinkles or edges and could generate higher ROS levels. As a result, GO-EPD exhibited optimal antibacterial activity against S. aureus, followed by GO-APS and GO-D. Keywords: Graphene oxide, Antibacterial, Titanium, Combination type, S. aureushttp://www.sciencedirect.com/science/article/pii/S2452199X18300136 |
| spellingShingle | Jiajun Qiu Lu Liu Hongqin Zhu Xuanyong Liu Combination types between graphene oxide and substrate affect the antibacterial activity Bioactive Materials |
| title | Combination types between graphene oxide and substrate affect the antibacterial activity |
| title_full | Combination types between graphene oxide and substrate affect the antibacterial activity |
| title_fullStr | Combination types between graphene oxide and substrate affect the antibacterial activity |
| title_full_unstemmed | Combination types between graphene oxide and substrate affect the antibacterial activity |
| title_short | Combination types between graphene oxide and substrate affect the antibacterial activity |
| title_sort | combination types between graphene oxide and substrate affect the antibacterial activity |
| url | http://www.sciencedirect.com/science/article/pii/S2452199X18300136 |
| work_keys_str_mv | AT jiajunqiu combinationtypesbetweengrapheneoxideandsubstrateaffecttheantibacterialactivity AT luliu combinationtypesbetweengrapheneoxideandsubstrateaffecttheantibacterialactivity AT hongqinzhu combinationtypesbetweengrapheneoxideandsubstrateaffecttheantibacterialactivity AT xuanyongliu combinationtypesbetweengrapheneoxideandsubstrateaffecttheantibacterialactivity |