Association of syntax score with short-term outcomes among acute ST-elevation myocardial infarction patients undergoing primary PCI
Objective: Syntax score (SX) has emerged as a reproducible angiographic tool to quantify the extent of coronary artery disease based on location and complexity of each lesion. It has been shown to predict long-term clinical outcomes in patients with left main or multi-vessel disease and recently als...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2017-04-01
|
| Series: | Indian Heart Journal |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0019483216303455 |
| _version_ | 1819098067503153152 |
|---|---|
| author | Sarita Choudhary |
| author_facet | Sarita Choudhary |
| author_sort | Sarita Choudhary |
| collection | DOAJ |
| description | Objective: Syntax score (SX) has emerged as a reproducible angiographic tool to quantify the extent of coronary artery disease based on location and complexity of each lesion. It has been shown to predict long-term clinical outcomes in patients with left main or multi-vessel disease and recently also in ST-segment elevation myocardial infarction undergoing primary PCI. The aim of this study was to evaluate whether the syntax score is associated with short-term cardiovascular outcomes in patients treated with primary percutaneous coronary intervention (PCI) for acute ST-segment elevation myocardial infarction (STEMI).
Methods: Syntax score was determined in 90 consecutive patients (mean age 54.2 ± 11.6) of STEMI undergoing primary PCI. Outcomes were stratified according to syntax score groups: SX low ≤15 (n = 33), SX mid 16–22 (n = 30), and SX high ≥23 (n = 27). The primary endpoint was all-cause mortality at 30 days. Secondary endpoints were nonfatal major adverse cardiac and cerebrovascular events (MACE) defined as a composite of any repeat revascularization, acute coronary syndrome, and stroke at 30 days in patients discharged alive.
Results: Mortality at 30 days was higher in the SX high group compared to the SX mid and SX low group (18.5% vs 3.3% p = 0.011), MACE at 30 days was higher in SX high group compared to SX mid and SX low group (48.1% vs 16.6% vs 9.1%, p = 0.001).
Conclusions: The syntax score is associated with 30-day mortality in patients with STEMI undergoing primary PCI. In those discharged, it is associated with risk of MACE at 30 days. |
| first_indexed | 2024-12-22T00:25:05Z |
| format | Article |
| id | doaj.art-21b1de8cca5a455f88c72c45893edde6 |
| institution | Directory Open Access Journal |
| issn | 0019-4832 |
| language | English |
| last_indexed | 2024-12-22T00:25:05Z |
| publishDate | 2017-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Indian Heart Journal |
| spelling | doaj.art-21b1de8cca5a455f88c72c45893edde62022-12-21T18:45:04ZengElsevierIndian Heart Journal0019-48322017-04-0169S1S20S2310.1016/j.ihj.2016.08.002Association of syntax score with short-term outcomes among acute ST-elevation myocardial infarction patients undergoing primary PCISarita ChoudharyObjective: Syntax score (SX) has emerged as a reproducible angiographic tool to quantify the extent of coronary artery disease based on location and complexity of each lesion. It has been shown to predict long-term clinical outcomes in patients with left main or multi-vessel disease and recently also in ST-segment elevation myocardial infarction undergoing primary PCI. The aim of this study was to evaluate whether the syntax score is associated with short-term cardiovascular outcomes in patients treated with primary percutaneous coronary intervention (PCI) for acute ST-segment elevation myocardial infarction (STEMI). Methods: Syntax score was determined in 90 consecutive patients (mean age 54.2 ± 11.6) of STEMI undergoing primary PCI. Outcomes were stratified according to syntax score groups: SX low ≤15 (n = 33), SX mid 16–22 (n = 30), and SX high ≥23 (n = 27). The primary endpoint was all-cause mortality at 30 days. Secondary endpoints were nonfatal major adverse cardiac and cerebrovascular events (MACE) defined as a composite of any repeat revascularization, acute coronary syndrome, and stroke at 30 days in patients discharged alive. Results: Mortality at 30 days was higher in the SX high group compared to the SX mid and SX low group (18.5% vs 3.3% p = 0.011), MACE at 30 days was higher in SX high group compared to SX mid and SX low group (48.1% vs 16.6% vs 9.1%, p = 0.001). Conclusions: The syntax score is associated with 30-day mortality in patients with STEMI undergoing primary PCI. In those discharged, it is associated with risk of MACE at 30 days.http://www.sciencedirect.com/science/article/pii/S0019483216303455SYNTAX scorePCIMyocardial infarctionSTEMIMortality |
| spellingShingle | Sarita Choudhary Association of syntax score with short-term outcomes among acute ST-elevation myocardial infarction patients undergoing primary PCI Indian Heart Journal SYNTAX score PCI Myocardial infarction STEMI Mortality |
| title | Association of syntax score with short-term outcomes among acute ST-elevation myocardial infarction patients undergoing primary PCI |
| title_full | Association of syntax score with short-term outcomes among acute ST-elevation myocardial infarction patients undergoing primary PCI |
| title_fullStr | Association of syntax score with short-term outcomes among acute ST-elevation myocardial infarction patients undergoing primary PCI |
| title_full_unstemmed | Association of syntax score with short-term outcomes among acute ST-elevation myocardial infarction patients undergoing primary PCI |
| title_short | Association of syntax score with short-term outcomes among acute ST-elevation myocardial infarction patients undergoing primary PCI |
| title_sort | association of syntax score with short term outcomes among acute st elevation myocardial infarction patients undergoing primary pci |
| topic | SYNTAX score PCI Myocardial infarction STEMI Mortality |
| url | http://www.sciencedirect.com/science/article/pii/S0019483216303455 |
| work_keys_str_mv | AT saritachoudhary associationofsyntaxscorewithshorttermoutcomesamongacutestelevationmyocardialinfarctionpatientsundergoingprimarypci |