Invasive aspergillosis in a user of inhaled cocaine: rhinosinusitis with bone and cartilage destruction
Aspergillosis is an infection caused by saprophytic fungi of the genus Aspergillus, which typically occurs in immunosuppressed individuals, but has also been reported in immunocompetent patients. The main routes of entry are the respiratory tract, skin, cornea, and ear, and the infection may be loca...
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Medicina Tropical (SBMT)
2014-07-01
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| Series: | Revista da Sociedade Brasileira de Medicina Tropical |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822014000400533&lng=en&tlng=en |
| _version_ | 1818233257200713728 |
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| author | Luna Azulay-Abulafia Maria Auxiliadora Jeunon Sousa Andrea Pussanti Daniel Dal'Asta Coimbra Hernando Vega Fred Bernardes Filho |
| author_facet | Luna Azulay-Abulafia Maria Auxiliadora Jeunon Sousa Andrea Pussanti Daniel Dal'Asta Coimbra Hernando Vega Fred Bernardes Filho |
| author_sort | Luna Azulay-Abulafia |
| collection | DOAJ |
| description | Aspergillosis is an infection caused by saprophytic fungi of the genus Aspergillus, which typically occurs in immunosuppressed individuals, but has also been reported in immunocompetent patients. The main routes of entry are the respiratory tract, skin, cornea, and ear, and the infection may be localized or disseminated by contiguity or vascular invasion. We report a severe case of rhinosinusitis with cutaneous involvement, caused by invasive aspergillosis, in an immunocompetent user of inhaled cocaine. Invasive aspergillosis related to cocaine abuse has not yet been reported in the literature. After itraconazole treatment and surgical debridement, complete clinical remission was achieved. Nasal reconstruction with a skin graft over a silicone prosthesis resulted in a satisfactory esthetic outcome. |
| first_indexed | 2024-12-12T11:19:18Z |
| format | Article |
| id | doaj.art-21b21bae3cef4f38af17fcd8f7e316e8 |
| institution | Directory Open Access Journal |
| issn | 1678-9849 |
| language | English |
| last_indexed | 2024-12-12T11:19:18Z |
| publishDate | 2014-07-01 |
| publisher | Sociedade Brasileira de Medicina Tropical (SBMT) |
| record_format | Article |
| series | Revista da Sociedade Brasileira de Medicina Tropical |
| spelling | doaj.art-21b21bae3cef4f38af17fcd8f7e316e82022-12-22T00:26:04ZengSociedade Brasileira de Medicina Tropical (SBMT)Revista da Sociedade Brasileira de Medicina Tropical1678-98492014-07-0147453353610.1590/0037-8682-0086-2014S0037-86822014000400533Invasive aspergillosis in a user of inhaled cocaine: rhinosinusitis with bone and cartilage destructionLuna Azulay-AbulafiaMaria Auxiliadora Jeunon SousaAndrea PussantiDaniel Dal'Asta CoimbraHernando VegaFred Bernardes FilhoAspergillosis is an infection caused by saprophytic fungi of the genus Aspergillus, which typically occurs in immunosuppressed individuals, but has also been reported in immunocompetent patients. The main routes of entry are the respiratory tract, skin, cornea, and ear, and the infection may be localized or disseminated by contiguity or vascular invasion. We report a severe case of rhinosinusitis with cutaneous involvement, caused by invasive aspergillosis, in an immunocompetent user of inhaled cocaine. Invasive aspergillosis related to cocaine abuse has not yet been reported in the literature. After itraconazole treatment and surgical debridement, complete clinical remission was achieved. Nasal reconstruction with a skin graft over a silicone prosthesis resulted in a satisfactory esthetic outcome.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822014000400533&lng=en&tlng=enAspergillosisAspergillus flavusRhinosinusitisCocaine addiction |
| spellingShingle | Luna Azulay-Abulafia Maria Auxiliadora Jeunon Sousa Andrea Pussanti Daniel Dal'Asta Coimbra Hernando Vega Fred Bernardes Filho Invasive aspergillosis in a user of inhaled cocaine: rhinosinusitis with bone and cartilage destruction Revista da Sociedade Brasileira de Medicina Tropical Aspergillosis Aspergillus flavus Rhinosinusitis Cocaine addiction |
| title | Invasive aspergillosis in a user of inhaled cocaine: rhinosinusitis with bone and cartilage destruction |
| title_full | Invasive aspergillosis in a user of inhaled cocaine: rhinosinusitis with bone and cartilage destruction |
| title_fullStr | Invasive aspergillosis in a user of inhaled cocaine: rhinosinusitis with bone and cartilage destruction |
| title_full_unstemmed | Invasive aspergillosis in a user of inhaled cocaine: rhinosinusitis with bone and cartilage destruction |
| title_short | Invasive aspergillosis in a user of inhaled cocaine: rhinosinusitis with bone and cartilage destruction |
| title_sort | invasive aspergillosis in a user of inhaled cocaine rhinosinusitis with bone and cartilage destruction |
| topic | Aspergillosis Aspergillus flavus Rhinosinusitis Cocaine addiction |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822014000400533&lng=en&tlng=en |
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