Pharmacogenetics in the Treatment of Huntington’s Disease: Review and Future Perspectives

Pharmacogenetics in the Treatment of Huntington’s Disease: Review and Future Perspectives

Huntington’s disease (HD) is an autosomal dominant progressive brain disorder, caused by a pathological expansion of a CAG repeat that encodes the huntingtin gene. This genetic neurodegenerative rare disease is characterized by cognitive, motor, and neuropsychiatric manifestations. The aim of the tr...

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Bibliographic Details
Main Authors: Xandra García-González, Esther Cubo, Lucía Simón-Vicente, Natividad Mariscal, Raquel Alcaraz, Laura Aguado, Jéssica Rivadeneyra-Posadas, Antonio Sanz-Solas, Miriam Saiz-Rodríguez
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Journal of Personalized Medicine
Subjects:
Huntington
pharmacogenetics
antichoreic
antidepressant
antipsychotic
Online Access:https://www.mdpi.com/2075-4426/13/3/385

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