Atrophic pseudoarthrosis. Effect of application of extracorporeal shock waves in an experimental model in tibia of rabbits.
Introduction The effects of extracorporeal shock wave therapy (ESWT) have been investigated in: human osteoblasts, fracture foci, non union and periosteum cells. The best results of non union treatment with ESWT have been documented for hypertrophic type. The objective of this study is to investiga...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Asociación Argentina de Ortopedia y Traumatología
2017-11-01
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| Series: | Revista de la Asociación Argentina de Ortopedia y Traumatología |
| Subjects: | |
| Online Access: | https://ojs.aaot.org.ar/ojsr/index.php/AAOTMAG/article/view/706 |
| _version_ | 1797429403715633152 |
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| author | Jorge Javier del Vecchio Marcos Galli Serra Rafael Martínez Gallino Juan Pablo Guyot Diego Amadeo Piazza Nicolás Raimondi Martín Caloia Eduardo Santini Araujo Carlos María Autorino |
| author_facet | Jorge Javier del Vecchio Marcos Galli Serra Rafael Martínez Gallino Juan Pablo Guyot Diego Amadeo Piazza Nicolás Raimondi Martín Caloia Eduardo Santini Araujo Carlos María Autorino |
| author_sort | Jorge Javier del Vecchio |
| collection | DOAJ |
| description | Introduction
The effects of extracorporeal shock wave therapy (ESWT) have been investigated in: human osteoblasts, fracture foci, non union and periosteum cells. The best results of non union treatment with ESWT have been documented for hypertrophic type. The objective of this study is to investigate the effects of ESWT in an atrophic non union focus generated in a rabbit tibia model.
Methods
Three groups were included: a) Group A: fractures receiving extracorporeal shock wave therapy (ESWT); b) Group B: (“control”): fractures not receiving ESWT; c) Group C: no fractures (right leg). Staining with hematoxylin-eosin was performed. ESWT included one session of 2000 extracorporeal shock wave impacts at 10 kV. A biomechanical analysis with a 3-point loading system was performed. Eighteen samples were included in the biomechanical study, 7 in Group A, 3 in Group B and 8 in group C. The samples were placed between two 19 mm cylindrical supports which were 75 mm apart, oriented concentrically to the compression punch.
Results
The histological test evidenced signs of union - periosteal and endosteal fracture callus - which were considerably larger in the tibias in Group A (treated with extracorporeal shock wave therapy) as compared to the control group (Group B). The maximum load for the healthy tibia Group (Group C) was higher as compared to Groups A (p<0.001; t:7.988) and B (p<0.001; t:6.599).
Conclusion
This report shows a significant radiographic and histological changes after focus intervention with application of ESWT. |
| first_indexed | 2024-03-09T09:12:40Z |
| format | Article |
| id | doaj.art-21b55199cb1747d8baf712865476b40e |
| institution | Directory Open Access Journal |
| issn | 1515-1786 1852-7434 |
| language | English |
| last_indexed | 2024-03-09T09:12:40Z |
| publishDate | 2017-11-01 |
| publisher | Asociación Argentina de Ortopedia y Traumatología |
| record_format | Article |
| series | Revista de la Asociación Argentina de Ortopedia y Traumatología |
| spelling | doaj.art-21b55199cb1747d8baf712865476b40e2023-12-02T08:12:17ZengAsociación Argentina de Ortopedia y TraumatologíaRevista de la Asociación Argentina de Ortopedia y Traumatología1515-17861852-74342017-11-0182432132610.15417/706322Atrophic pseudoarthrosis. Effect of application of extracorporeal shock waves in an experimental model in tibia of rabbits.Jorge Javier del Vecchio0Marcos Galli Serra1Rafael Martínez Gallino2Juan Pablo Guyot3Diego Amadeo Piazza4Nicolás Raimondi5Martín Caloia6Eduardo Santini Araujo7Carlos María Autorino8Fundación FavaloroHospital Universitario AustralClínica Romagosa Sanatorio AllendeHospital Universitario AustralFundación FavaloroHospital Universitario AustralHospital Universitario AustralLaboratorio de Patología Ortopédica.Hospital Universitario AustralIntroduction The effects of extracorporeal shock wave therapy (ESWT) have been investigated in: human osteoblasts, fracture foci, non union and periosteum cells. The best results of non union treatment with ESWT have been documented for hypertrophic type. The objective of this study is to investigate the effects of ESWT in an atrophic non union focus generated in a rabbit tibia model. Methods Three groups were included: a) Group A: fractures receiving extracorporeal shock wave therapy (ESWT); b) Group B: (“control”): fractures not receiving ESWT; c) Group C: no fractures (right leg). Staining with hematoxylin-eosin was performed. ESWT included one session of 2000 extracorporeal shock wave impacts at 10 kV. A biomechanical analysis with a 3-point loading system was performed. Eighteen samples were included in the biomechanical study, 7 in Group A, 3 in Group B and 8 in group C. The samples were placed between two 19 mm cylindrical supports which were 75 mm apart, oriented concentrically to the compression punch. Results The histological test evidenced signs of union - periosteal and endosteal fracture callus - which were considerably larger in the tibias in Group A (treated with extracorporeal shock wave therapy) as compared to the control group (Group B). The maximum load for the healthy tibia Group (Group C) was higher as compared to Groups A (p<0.001; t:7.988) and B (p<0.001; t:6.599). Conclusion This report shows a significant radiographic and histological changes after focus intervention with application of ESWT.https://ojs.aaot.org.ar/ojsr/index.php/AAOTMAG/article/view/706Pseudoartrosis, OCEC, tibia, conejo. Pseudarthrosisextracorporeal shock wavestibiarabbit. |
| spellingShingle | Jorge Javier del Vecchio Marcos Galli Serra Rafael Martínez Gallino Juan Pablo Guyot Diego Amadeo Piazza Nicolás Raimondi Martín Caloia Eduardo Santini Araujo Carlos María Autorino Atrophic pseudoarthrosis. Effect of application of extracorporeal shock waves in an experimental model in tibia of rabbits. Revista de la Asociación Argentina de Ortopedia y Traumatología Pseudoartrosis, OCEC, tibia, conejo. Pseudarthrosis extracorporeal shock waves tibia rabbit. |
| title | Atrophic pseudoarthrosis. Effect of application of extracorporeal shock waves in an experimental model in tibia of rabbits. |
| title_full | Atrophic pseudoarthrosis. Effect of application of extracorporeal shock waves in an experimental model in tibia of rabbits. |
| title_fullStr | Atrophic pseudoarthrosis. Effect of application of extracorporeal shock waves in an experimental model in tibia of rabbits. |
| title_full_unstemmed | Atrophic pseudoarthrosis. Effect of application of extracorporeal shock waves in an experimental model in tibia of rabbits. |
| title_short | Atrophic pseudoarthrosis. Effect of application of extracorporeal shock waves in an experimental model in tibia of rabbits. |
| title_sort | atrophic pseudoarthrosis effect of application of extracorporeal shock waves in an experimental model in tibia of rabbits |
| topic | Pseudoartrosis, OCEC, tibia, conejo. Pseudarthrosis extracorporeal shock waves tibia rabbit. |
| url | https://ojs.aaot.org.ar/ojsr/index.php/AAOTMAG/article/view/706 |
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