An encounter with potentially reemerging chikungunya infection during 2016-2017
Background: Chikungunya (CHIK) virus infection is an arthropod-borne “reemerging” zoonotic disease. Our geographical region reported almost negligible cases during 20112015; however, in the latter part of 2016 and early 2017, Chandigarh experienced a major outbreak of CHIK infection. The present ret...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2022-01-01
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| Series: | Apollo Medicine |
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| Online Access: | http://www.apollomedicine.org/article.asp?issn=0976-0016;year=2022;volume=19;issue=4;spage=241;epage=244;aulast=Singla |
| _version_ | 1811200615074758656 |
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| author | Nidhi Singla Monica Gupta Gursimran Kaur Mohi |
| author_facet | Nidhi Singla Monica Gupta Gursimran Kaur Mohi |
| author_sort | Nidhi Singla |
| collection | DOAJ |
| description | Background: Chikungunya (CHIK) virus infection is an arthropod-borne “reemerging” zoonotic disease. Our geographical region reported almost negligible cases during 20112015; however, in the latter part of 2016 and early 2017, Chandigarh experienced a major outbreak of CHIK infection. The present retrospective observational study was undertaken to examine the seroprevalence and clinical profile of all the adult patients suspected of CHIK presenting to our hospital from 2016 to 2017. Materials and Methods: All consecutive patients with clinical suspicion of CHIK infection were included in the study. Serum samples were collected from all the adult patients and tested for IgM antibodies by enzyme-linked immunosorbent assay using commercially available kits. Results: Out of 1087 clinically suspected adult patients, 351 (32.29%) were found to be positive for CHIK IgM antibodies. Males 208 (59.2%) outnumbered the females 143 (40.7%). Family clustering was common. All patients presented with fever, severe joint pains (95.7%), and joint stiffness and swelling (69.8%). Two patients presented with encephalitis. Conclusion: CHIK is a reemerging debilitating arthritic disease of global health concern with a capacity for immeasurable morbidity. In the absence of a licensed vaccine or chemoprophylaxis, active surveillance and vector control are the key factors in limiting the disease outbreak and transmission. |
| first_indexed | 2024-04-12T02:06:33Z |
| format | Article |
| id | doaj.art-21b7034c6e5b4de289ac3b842584b79b |
| institution | Directory Open Access Journal |
| issn | 0976-0016 2213-3682 |
| language | English |
| last_indexed | 2024-04-12T02:06:33Z |
| publishDate | 2022-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Apollo Medicine |
| spelling | doaj.art-21b7034c6e5b4de289ac3b842584b79b2022-12-22T03:52:30ZengWolters Kluwer Medknow PublicationsApollo Medicine0976-00162213-36822022-01-0119424124410.4103/am.am_98_22An encounter with potentially reemerging chikungunya infection during 2016-2017Nidhi SinglaMonica GuptaGursimran Kaur MohiBackground: Chikungunya (CHIK) virus infection is an arthropod-borne “reemerging” zoonotic disease. Our geographical region reported almost negligible cases during 20112015; however, in the latter part of 2016 and early 2017, Chandigarh experienced a major outbreak of CHIK infection. The present retrospective observational study was undertaken to examine the seroprevalence and clinical profile of all the adult patients suspected of CHIK presenting to our hospital from 2016 to 2017. Materials and Methods: All consecutive patients with clinical suspicion of CHIK infection were included in the study. Serum samples were collected from all the adult patients and tested for IgM antibodies by enzyme-linked immunosorbent assay using commercially available kits. Results: Out of 1087 clinically suspected adult patients, 351 (32.29%) were found to be positive for CHIK IgM antibodies. Males 208 (59.2%) outnumbered the females 143 (40.7%). Family clustering was common. All patients presented with fever, severe joint pains (95.7%), and joint stiffness and swelling (69.8%). Two patients presented with encephalitis. Conclusion: CHIK is a reemerging debilitating arthritic disease of global health concern with a capacity for immeasurable morbidity. In the absence of a licensed vaccine or chemoprophylaxis, active surveillance and vector control are the key factors in limiting the disease outbreak and transmission.http://www.apollomedicine.org/article.asp?issn=0976-0016;year=2022;volume=19;issue=4;spage=241;epage=244;aulast=Singlaarboviruschandigarhchikungunyaclinical featuresreemerging infectionseroprevalence |
| spellingShingle | Nidhi Singla Monica Gupta Gursimran Kaur Mohi An encounter with potentially reemerging chikungunya infection during 2016-2017 Apollo Medicine arbovirus chandigarh chikungunya clinical features reemerging infection seroprevalence |
| title | An encounter with potentially reemerging chikungunya infection during 2016-2017 |
| title_full | An encounter with potentially reemerging chikungunya infection during 2016-2017 |
| title_fullStr | An encounter with potentially reemerging chikungunya infection during 2016-2017 |
| title_full_unstemmed | An encounter with potentially reemerging chikungunya infection during 2016-2017 |
| title_short | An encounter with potentially reemerging chikungunya infection during 2016-2017 |
| title_sort | encounter with potentially reemerging chikungunya infection during 2016 2017 |
| topic | arbovirus chandigarh chikungunya clinical features reemerging infection seroprevalence |
| url | http://www.apollomedicine.org/article.asp?issn=0976-0016;year=2022;volume=19;issue=4;spage=241;epage=244;aulast=Singla |
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