Probing the relevance of the accelerated aging mouse line SAMP8 as a model for certain types of neuropsychiatric symptoms in dementia

Probing the relevance of the accelerated aging mouse line SAMP8 as a model for certain types of neuropsychiatric symptoms in dementia

IntroductionPeople with dementia (PwD) often present with neuropsychiatric symptoms (NPS). NPS are of substantial burden to the patients, and current treatment options are unsatisfactory. Investigators searching for novel medications need animal models that present disease-relevant phenotypes and ca...

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Hlavní autoři: Giorgio Bergamini, Helene Massinet, Aaron Hart, Sean Durkin, Gabin Pierlot, Michel Alexander Steiner
Médium: Článek
Jazyk:English
Vydáno: Frontiers Media S.A. 2023-02-01
Edice:Frontiers in Psychiatry
Témata:
dementia
agitation
aggression
sociability
SAMP8 mice
deep learning
On-line přístup:https://www.frontiersin.org/articles/10.3389/fpsyt.2023.1054163/full

Internet

https://www.frontiersin.org/articles/10.3389/fpsyt.2023.1054163/full

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