Recent Progress on Circular RNAs in the Development of Skeletal Muscle and Adipose Tissues of Farm Animals
Circular RNAs (circRNAs) are a highly conserved and specifically expressed novel class of covalently closed non-coding RNAs. CircRNAs can function as miRNA sponges, protein scaffolds, and regulatory factors, and play various roles in development and other biological processes in mammals. With the ra...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-02-01
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| Series: | Biomolecules |
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| Online Access: | https://www.mdpi.com/2218-273X/13/2/314 |
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| author | Shanying Yan Yangli Pei Jiju Li Zhonglin Tang Yalan Yang |
| author_facet | Shanying Yan Yangli Pei Jiju Li Zhonglin Tang Yalan Yang |
| author_sort | Shanying Yan |
| collection | DOAJ |
| description | Circular RNAs (circRNAs) are a highly conserved and specifically expressed novel class of covalently closed non-coding RNAs. CircRNAs can function as miRNA sponges, protein scaffolds, and regulatory factors, and play various roles in development and other biological processes in mammals. With the rapid development of high-throughput sequencing technology, thousands of circRNAs have been discovered in farm animals; some reportedly play vital roles in skeletal muscle and adipose development. These are critical factors affecting meat yield and quality. In this review, we have highlighted the recent advances in circRNA-related studies of skeletal muscle and adipose in farm animals. We have also described the biogenesis, properties, and biological functions of circRNAs. Furthermore, we have comprehensively summarized the functions and regulatory mechanisms of circRNAs in skeletal muscle and adipose development in farm animals and their effects on economic traits such as meat yield and quality. Finally, we propose that circRNAs are putative novel targets to improve meat yield and quality traits during animal breeding. |
| first_indexed | 2024-03-11T09:05:43Z |
| format | Article |
| id | doaj.art-21bb42e6263648f599aacd461c1b420f |
| institution | Directory Open Access Journal |
| issn | 2218-273X |
| language | English |
| last_indexed | 2024-03-11T09:05:43Z |
| publishDate | 2023-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biomolecules |
| spelling | doaj.art-21bb42e6263648f599aacd461c1b420f2023-11-16T19:23:25ZengMDPI AGBiomolecules2218-273X2023-02-0113231410.3390/biom13020314Recent Progress on Circular RNAs in the Development of Skeletal Muscle and Adipose Tissues of Farm AnimalsShanying Yan0Yangli Pei1Jiju Li2Zhonglin Tang3Yalan Yang4Guangdong Provincial Key Laboratory of Animal Molecular Design and Precise Breeding, Key Laboratory of Animal Molecular Design and Precise Breeding of Guangdong Higher Education Institutes, School of Life Science and Engineering, Foshan University, Foshan 528231, ChinaGuangdong Provincial Key Laboratory of Animal Molecular Design and Precise Breeding, Key Laboratory of Animal Molecular Design and Precise Breeding of Guangdong Higher Education Institutes, School of Life Science and Engineering, Foshan University, Foshan 528231, ChinaGuangdong Provincial Key Laboratory of Animal Molecular Design and Precise Breeding, Key Laboratory of Animal Molecular Design and Precise Breeding of Guangdong Higher Education Institutes, School of Life Science and Engineering, Foshan University, Foshan 528231, ChinaShenzhen Branch, Guangdong Laboratory for Lingnan Modern Agriculture, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen 518124, ChinaShenzhen Branch, Guangdong Laboratory for Lingnan Modern Agriculture, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen 518124, ChinaCircular RNAs (circRNAs) are a highly conserved and specifically expressed novel class of covalently closed non-coding RNAs. CircRNAs can function as miRNA sponges, protein scaffolds, and regulatory factors, and play various roles in development and other biological processes in mammals. With the rapid development of high-throughput sequencing technology, thousands of circRNAs have been discovered in farm animals; some reportedly play vital roles in skeletal muscle and adipose development. These are critical factors affecting meat yield and quality. In this review, we have highlighted the recent advances in circRNA-related studies of skeletal muscle and adipose in farm animals. We have also described the biogenesis, properties, and biological functions of circRNAs. Furthermore, we have comprehensively summarized the functions and regulatory mechanisms of circRNAs in skeletal muscle and adipose development in farm animals and their effects on economic traits such as meat yield and quality. Finally, we propose that circRNAs are putative novel targets to improve meat yield and quality traits during animal breeding.https://www.mdpi.com/2218-273X/13/2/314circRNAsanimalskeletal muscleadiposedevelopment and growth |
| spellingShingle | Shanying Yan Yangli Pei Jiju Li Zhonglin Tang Yalan Yang Recent Progress on Circular RNAs in the Development of Skeletal Muscle and Adipose Tissues of Farm Animals Biomolecules circRNAs animal skeletal muscle adipose development and growth |
| title | Recent Progress on Circular RNAs in the Development of Skeletal Muscle and Adipose Tissues of Farm Animals |
| title_full | Recent Progress on Circular RNAs in the Development of Skeletal Muscle and Adipose Tissues of Farm Animals |
| title_fullStr | Recent Progress on Circular RNAs in the Development of Skeletal Muscle and Adipose Tissues of Farm Animals |
| title_full_unstemmed | Recent Progress on Circular RNAs in the Development of Skeletal Muscle and Adipose Tissues of Farm Animals |
| title_short | Recent Progress on Circular RNAs in the Development of Skeletal Muscle and Adipose Tissues of Farm Animals |
| title_sort | recent progress on circular rnas in the development of skeletal muscle and adipose tissues of farm animals |
| topic | circRNAs animal skeletal muscle adipose development and growth |
| url | https://www.mdpi.com/2218-273X/13/2/314 |
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