A SARS-CoV-2 Wuhan spike virosome vaccine induces superior neutralization breadth compared to one using the Beta spike

A SARS-CoV-2 Wuhan spike virosome vaccine induces superior neutralization breadth compared to one using the Beta spike

Abstract Current SARS-CoV-2 vaccines are effective, but long-term protection is threatened by the emergence of virus variants. We generated a virosome vaccine containing the Beta spike protein and compared its immunogenicity in mice to a virosome vaccine containing the original Wuhan spike. Two admi...

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Bibliographic Details
Main Authors: Yme U. van der Velden, Marloes Grobben, Tom G. Caniels, Judith A. Burger, Meliawati Poniman, Melissa Oomen, Esther Siteur-van Rijnstra, Khadija Tejjani, Denise Guerra, Ronald Kempers, Toon Stegmann, Marit J. van Gils, Rogier W. Sanders
Format: Article
Language:English
Published: Nature Portfolio 2022-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-07590-w

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