High-Resolution Splenic Imaging: [<sup>68</sup>Ga]Ga-Oxine Red Blood Cell PET/CT for Differentiation of Splenosis Mimicking Malignant Lymphoma

The differentiation of splenic tissue from malignant lesions via imaging may be challenging, particularly considering aberrant or accessory lesions and diseases that are rarely encountered. Functioning splenic tissue can be identified using technetium-99m red blood cell (<sup>99m</sup>Tc...

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Bibliographic Details
Main Authors: Anke Werner, Martin Freesmeyer, Robert Drescher
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Tomography
Subjects:
Online Access:https://www.mdpi.com/2379-139X/8/6/244
Description
Summary:The differentiation of splenic tissue from malignant lesions via imaging may be challenging, particularly considering aberrant or accessory lesions and diseases that are rarely encountered. Functioning splenic tissue can be identified using technetium-99m red blood cell (<sup>99m</sup>Tc-RBC) scintigraphy, but its sensitivity is limited and may not be available. We present the case of a patient in whom disseminated abdomino-pelvic splenosis was diagnosed using PET/CT with gallium-68-oxine-labeled RBCs. The method represents a feasible and probably superior alternative to splenic scintigraphy.
ISSN:2379-1381
2379-139X