High-Resolution Splenic Imaging: [<sup>68</sup>Ga]Ga-Oxine Red Blood Cell PET/CT for Differentiation of Splenosis Mimicking Malignant Lymphoma
The differentiation of splenic tissue from malignant lesions via imaging may be challenging, particularly considering aberrant or accessory lesions and diseases that are rarely encountered. Functioning splenic tissue can be identified using technetium-99m red blood cell (<sup>99m</sup>Tc...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-12-01
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| Series: | Tomography |
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| Online Access: | https://www.mdpi.com/2379-139X/8/6/244 |
| _version_ | 1797455086245380096 |
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| author | Anke Werner Martin Freesmeyer Robert Drescher |
| author_facet | Anke Werner Martin Freesmeyer Robert Drescher |
| author_sort | Anke Werner |
| collection | DOAJ |
| description | The differentiation of splenic tissue from malignant lesions via imaging may be challenging, particularly considering aberrant or accessory lesions and diseases that are rarely encountered. Functioning splenic tissue can be identified using technetium-99m red blood cell (<sup>99m</sup>Tc-RBC) scintigraphy, but its sensitivity is limited and may not be available. We present the case of a patient in whom disseminated abdomino-pelvic splenosis was diagnosed using PET/CT with gallium-68-oxine-labeled RBCs. The method represents a feasible and probably superior alternative to splenic scintigraphy. |
| first_indexed | 2024-03-09T15:47:26Z |
| format | Article |
| id | doaj.art-21c0ae7f4f944ba0bb52a23fe6940006 |
| institution | Directory Open Access Journal |
| issn | 2379-1381 2379-139X |
| language | English |
| last_indexed | 2024-03-09T15:47:26Z |
| publishDate | 2022-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Tomography |
| spelling | doaj.art-21c0ae7f4f944ba0bb52a23fe69400062023-11-24T18:24:16ZengMDPI AGTomography2379-13812379-139X2022-12-01862915291810.3390/tomography8060244High-Resolution Splenic Imaging: [<sup>68</sup>Ga]Ga-Oxine Red Blood Cell PET/CT for Differentiation of Splenosis Mimicking Malignant LymphomaAnke Werner0Martin Freesmeyer1Robert Drescher2Clinic of Nuclear Medicine, Jena University Hospital, 07747 Jena, GermanyClinic of Nuclear Medicine, Jena University Hospital, 07747 Jena, GermanyClinic of Nuclear Medicine, Jena University Hospital, 07747 Jena, GermanyThe differentiation of splenic tissue from malignant lesions via imaging may be challenging, particularly considering aberrant or accessory lesions and diseases that are rarely encountered. Functioning splenic tissue can be identified using technetium-99m red blood cell (<sup>99m</sup>Tc-RBC) scintigraphy, but its sensitivity is limited and may not be available. We present the case of a patient in whom disseminated abdomino-pelvic splenosis was diagnosed using PET/CT with gallium-68-oxine-labeled RBCs. The method represents a feasible and probably superior alternative to splenic scintigraphy.https://www.mdpi.com/2379-139X/8/6/244PET/CTradiotracersspleenerythrocytesoxineoxyquinoline |
| spellingShingle | Anke Werner Martin Freesmeyer Robert Drescher High-Resolution Splenic Imaging: [<sup>68</sup>Ga]Ga-Oxine Red Blood Cell PET/CT for Differentiation of Splenosis Mimicking Malignant Lymphoma Tomography PET/CT radiotracers spleen erythrocytes oxine oxyquinoline |
| title | High-Resolution Splenic Imaging: [<sup>68</sup>Ga]Ga-Oxine Red Blood Cell PET/CT for Differentiation of Splenosis Mimicking Malignant Lymphoma |
| title_full | High-Resolution Splenic Imaging: [<sup>68</sup>Ga]Ga-Oxine Red Blood Cell PET/CT for Differentiation of Splenosis Mimicking Malignant Lymphoma |
| title_fullStr | High-Resolution Splenic Imaging: [<sup>68</sup>Ga]Ga-Oxine Red Blood Cell PET/CT for Differentiation of Splenosis Mimicking Malignant Lymphoma |
| title_full_unstemmed | High-Resolution Splenic Imaging: [<sup>68</sup>Ga]Ga-Oxine Red Blood Cell PET/CT for Differentiation of Splenosis Mimicking Malignant Lymphoma |
| title_short | High-Resolution Splenic Imaging: [<sup>68</sup>Ga]Ga-Oxine Red Blood Cell PET/CT for Differentiation of Splenosis Mimicking Malignant Lymphoma |
| title_sort | high resolution splenic imaging sup 68 sup ga ga oxine red blood cell pet ct for differentiation of splenosis mimicking malignant lymphoma |
| topic | PET/CT radiotracers spleen erythrocytes oxine oxyquinoline |
| url | https://www.mdpi.com/2379-139X/8/6/244 |
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