An Evaluation of the Numbers and Locations of Coronary Artery Disease with Some of the Major Atherosclerotic Risk Factors in Patients with Coronary Artery Disease
Introduction: Despite definite recognition of major atherosclerotic risk factors, the relationship between the pattern of coronary artery disease and these risk factors is unknown. Aim: The aim of this study was to identify the relationship between some of the major atherosclerotic risk factors...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2017-08-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/10460/29104_CE[Ra]_F(Sh)_PF1(NE_VT_GG)_PFA(NE_SS).pdf |
| Summary: | Introduction: Despite definite recognition of major
atherosclerotic risk factors, the relationship between the pattern
of coronary artery disease and these risk factors is unknown.
Aim: The aim of this study was to identify the relationship
between some of the major atherosclerotic risk factors and the
number and pattern of coronary artery disease in patients with
coronary artery disease who presented to Farshchian Heart
University Hospital, Hamadan, Iran.
Materials and Methods: In this descriptive cross-sectional
study, we investigated some of the major atherosclerotic risk
factors and their relationships with the type of coronary artery
disease in terms of number and location of disease. A total
of 1100 patients were enrolled with coronary artery disease
confirmed by selective coronary angiography from 2010-2014.
A p-value<0.05 was considered statistically significant.
Results: A total of 1100 patients enrolled in this study. The
patient population consisted of 743 (67.5%) males and 357
(32.5%) females. A meaningful relationship existed between
ageing, diabetes mellitus, hypertension and 3-Vessel Disease
(3VD, p<0.001) as well as between hyperlipidemia and Single
Vessel Disease (SVD, p<0.001). Patients diagnosed with
diabetes mellitus, hypertension, and hyperlipidemia showed
greater potential to develop coronary artery disease at the
proximal section of the coronary arteries.
Conclusion: Based on the relationship between some of the
major risk factors and the pattern of coronary artery disease in
the current study, prospective studies should investigate other
risk factors. We recommend that a plan should be developed
to reduce adjustable risk factors such as diabetes mellitus,
hypertension and hyperlipidemia in order to decrease coronary
artery disease. |
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| ISSN: | 2249-782X 0973-709X |