Production and bioprocessing of Taxol from Aspergillus niger, an endophyte of Encephalartos whitelockii, with a plausible biosynthetic stability: antiproliferative activity and cell cycle analysis

Production and bioprocessing of Taxol from Aspergillus niger, an endophyte of Encephalartos whitelockii, with a plausible biosynthetic stability: antiproliferative activity and cell cycle analysis

Abstract The biosynthetic potency of Taxol by fungi raises their prospective to be a platform for commercial production of Taxol, nevertheless, the attenuation of its productivity with the fungal storage, is the challenge. Thus, screening for a novel fungal isolate inhabiting ethnopharmacological pl...

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Bibliographic Details
Main Authors: Asmaa Gamal, Eman Fikry, Nora Tawfeek, Azza M. El-Shafae, Ashraf S. A. El-Sayed, Maher M. El-Domiaty
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Microbial Cell Factories
Subjects:
Taxol
Aspergillus niger
Encephalartos whitelockii
Antiproliferative activity
Wound healing
Cell cycle analysis
Online Access:https://doi.org/10.1186/s12934-024-02356-7

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