The lncRNA Connection Between Cellular Metabolism and Epigenetics in Trained Immunity

The lncRNA Connection Between Cellular Metabolism and Epigenetics in Trained Immunity

Trained immunity describes the ability of innate immune cells to form immunological memories of prior encounters with pathogens. Recollection of these memories during a secondary encounter manifests a broadly enhanced inflammatory response characterized by the increased transcription of innate immun...

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Bibliographic Details
Main Authors: Ezio T. Fok, Laurianne Davignon, Stephanie Fanucchi, Musa M. Mhlanga
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Immunology
Subjects:
trained immunity
epigenetics
metabolism
long non-coding
inflammation
nuclear architecture
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.03184/full

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