Prevalence and Factors Associated with Diabetic Retinopathy among Adult Diabetes Patients in Southeast Ethiopia: A Hospital-Based Cross-Sectional Study
Biniyam Sahiledengle,1 Tesfaye Assefa,2 Wogene Negash,2 Anwar Tahir,2 Tadele Regasa,3 Yohannes Tekalegn,1 Ayele Mamo,4 Zinash Teferu,1 Damtew Solomon,3 Habtamu Gezahegn,3 Kebebe Bekele,5 Demisu Zenbaba,1 Alelign Tasew,1 Fikreab Desta,1 Zegeye Regassa,2 Zegeye Feleke,2 Chala Kene,6 Fekata Tolcha,7 De...
| Main Authors: | , , , , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Dove Medical Press
2022-10-01
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| Series: | Clinical Ophthalmology |
| Subjects: | |
| Online Access: | https://www.dovepress.com/prevalence-and-factors-associated-with-diabetic-retinopathy-among-adul-peer-reviewed-fulltext-article-OPTH |
| _version_ | 1811344612355211264 |
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| author | Sahiledengle B Assefa T Negash W Tahir A Regasa T Tekalegn Y Mamo A Teferu Z Solomon D Gezahegn H Bekele K Zenbaba D Tasew A Desta F Regassa Z Feleke Z Kene C Tolcha F Gomora D Dibaba D Atlaw D |
| author_facet | Sahiledengle B Assefa T Negash W Tahir A Regasa T Tekalegn Y Mamo A Teferu Z Solomon D Gezahegn H Bekele K Zenbaba D Tasew A Desta F Regassa Z Feleke Z Kene C Tolcha F Gomora D Dibaba D Atlaw D |
| author_sort | Sahiledengle B |
| collection | DOAJ |
| description | Biniyam Sahiledengle,1 Tesfaye Assefa,2 Wogene Negash,2 Anwar Tahir,2 Tadele Regasa,3 Yohannes Tekalegn,1 Ayele Mamo,4 Zinash Teferu,1 Damtew Solomon,3 Habtamu Gezahegn,3 Kebebe Bekele,5 Demisu Zenbaba,1 Alelign Tasew,1 Fikreab Desta,1 Zegeye Regassa,2 Zegeye Feleke,2 Chala Kene,6 Fekata Tolcha,7 Degefa Gomora,6 Diriba Dibaba,1 Daniel Atlaw3 1Public Health Department, Madda Walabu University, Goba Referral Hospital, Bale Goba, Ethiopia; 2Nursing Department, Madda Walabu University, Goba Referral Hospital, Bale Goba, Ethiopia; 3Biomedical Department, Madda Walabu University, Goba Referral Hospital, Bale Goba, Ethiopia; 4Pharmacy Department, Madda Walabu University, Goba Referral Hospital, Bale Goba, Ethiopia; 5Surgery Department, Madda Walabu University, Goba Referral Hospital, Bale Goba, Ethiopia; 6Midwifery of Department, Madda Walabu University, Goba Referral Hospital, Bale Goba, Ethiopia; 7Pediatrics and Child Health Department, Madda Walabu University, Goba Referral Hospital, Bale Goba, EthiopiaCorrespondence: Biniyam Sahiledengle, Public Health Department, Madda Walabu University, Goba Referral Hospital, Bale Goba, Ethiopia, Email biniyam.sahiledengle@gmail.comBackground: Diabetic retinopathy (DR) is the most prevalent microvascular consequence of diabetes mellitus, and it can result in blindness that is irreversible. Due to delayed diagnosis and limited access to diabetic care, the situation is even worse in developing countries. Scientific evidence on the prevalence of DR and its associated factors among diabetes patients in low-income countries, such as Ethiopia, is limited. This study aimed to determine the prevalence of DR and associated factors among adult diabetes patients in southeast Ethiopia.Methods: A hospital-based cross-sectional study was conducted among diabetes patients who visited Madda Walabu University Goba Referral Hospital. Fundus and slit-lamp examination were performed for screening of DR. Multivariate binary logistic regression was computed to identify factors associated with DR.Results: A total of 256 patients (144 men, 56.2%) aged 50.15± 15.71 years were included in the study. The prevalence of any DR was 19.9% (95% CI 15.4%– 25.3%), mild nonproliferative diabetic retinopathy (NPDR) 10.9% (95% CI 7.6%– 15.4%), moderate NPDR 5.9% (95% CI 3.5%– 9.5%), severe NPDR 0.9% (95% CI 0.2%– 3.9%), and proliferative DR 2.3% (95% CI 1.0%– 5.1%). Duration of diabetes ≥ 10 years (AOR 10.22, 95% CI 1.70– 61.44), central obesity (AOR 5.42, 95% CI 1.38– 21.19), overweight/obese (AOR 2.65, 95% CI 1.02– 6.92), lower high-density lipoprotein (HDL) cholesterol (AOR 5.82, 95% CI 1.86– 18.24), moderate triglyceride:HDL cholesterol ratio (AOR 4.13, 95% CI 1.13– 15.15), and urban dwelling (AOR 2.84, 95% CI 1.04– 7.78) were significantly associated with DR.Conclusion: One in every five DM patients had DR. Sociodemographic, anthropometric, and blood lipids were independently associated with DR. To reduce the burden of diabetes, strategies that focus on lifestyle modifications targeted at identified modifiable risk factors are essential.Keywords: diabetes mellitus, diabetic retinopathy, Ethiopia |
| first_indexed | 2024-04-13T19:50:44Z |
| format | Article |
| id | doaj.art-21c701a56a4c4f8a9abdb1f806b6fd38 |
| institution | Directory Open Access Journal |
| issn | 1177-5483 |
| language | English |
| last_indexed | 2024-04-13T19:50:44Z |
| publishDate | 2022-10-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Clinical Ophthalmology |
| spelling | doaj.art-21c701a56a4c4f8a9abdb1f806b6fd382022-12-22T02:32:33ZengDove Medical PressClinical Ophthalmology1177-54832022-10-01Volume 163527354579101Prevalence and Factors Associated with Diabetic Retinopathy among Adult Diabetes Patients in Southeast Ethiopia: A Hospital-Based Cross-Sectional StudySahiledengle BAssefa TNegash WTahir ARegasa TTekalegn YMamo ATeferu ZSolomon DGezahegn HBekele KZenbaba DTasew ADesta FRegassa ZFeleke ZKene CTolcha FGomora DDibaba DAtlaw DBiniyam Sahiledengle,1 Tesfaye Assefa,2 Wogene Negash,2 Anwar Tahir,2 Tadele Regasa,3 Yohannes Tekalegn,1 Ayele Mamo,4 Zinash Teferu,1 Damtew Solomon,3 Habtamu Gezahegn,3 Kebebe Bekele,5 Demisu Zenbaba,1 Alelign Tasew,1 Fikreab Desta,1 Zegeye Regassa,2 Zegeye Feleke,2 Chala Kene,6 Fekata Tolcha,7 Degefa Gomora,6 Diriba Dibaba,1 Daniel Atlaw3 1Public Health Department, Madda Walabu University, Goba Referral Hospital, Bale Goba, Ethiopia; 2Nursing Department, Madda Walabu University, Goba Referral Hospital, Bale Goba, Ethiopia; 3Biomedical Department, Madda Walabu University, Goba Referral Hospital, Bale Goba, Ethiopia; 4Pharmacy Department, Madda Walabu University, Goba Referral Hospital, Bale Goba, Ethiopia; 5Surgery Department, Madda Walabu University, Goba Referral Hospital, Bale Goba, Ethiopia; 6Midwifery of Department, Madda Walabu University, Goba Referral Hospital, Bale Goba, Ethiopia; 7Pediatrics and Child Health Department, Madda Walabu University, Goba Referral Hospital, Bale Goba, EthiopiaCorrespondence: Biniyam Sahiledengle, Public Health Department, Madda Walabu University, Goba Referral Hospital, Bale Goba, Ethiopia, Email biniyam.sahiledengle@gmail.comBackground: Diabetic retinopathy (DR) is the most prevalent microvascular consequence of diabetes mellitus, and it can result in blindness that is irreversible. Due to delayed diagnosis and limited access to diabetic care, the situation is even worse in developing countries. Scientific evidence on the prevalence of DR and its associated factors among diabetes patients in low-income countries, such as Ethiopia, is limited. This study aimed to determine the prevalence of DR and associated factors among adult diabetes patients in southeast Ethiopia.Methods: A hospital-based cross-sectional study was conducted among diabetes patients who visited Madda Walabu University Goba Referral Hospital. Fundus and slit-lamp examination were performed for screening of DR. Multivariate binary logistic regression was computed to identify factors associated with DR.Results: A total of 256 patients (144 men, 56.2%) aged 50.15± 15.71 years were included in the study. The prevalence of any DR was 19.9% (95% CI 15.4%– 25.3%), mild nonproliferative diabetic retinopathy (NPDR) 10.9% (95% CI 7.6%– 15.4%), moderate NPDR 5.9% (95% CI 3.5%– 9.5%), severe NPDR 0.9% (95% CI 0.2%– 3.9%), and proliferative DR 2.3% (95% CI 1.0%– 5.1%). Duration of diabetes ≥ 10 years (AOR 10.22, 95% CI 1.70– 61.44), central obesity (AOR 5.42, 95% CI 1.38– 21.19), overweight/obese (AOR 2.65, 95% CI 1.02– 6.92), lower high-density lipoprotein (HDL) cholesterol (AOR 5.82, 95% CI 1.86– 18.24), moderate triglyceride:HDL cholesterol ratio (AOR 4.13, 95% CI 1.13– 15.15), and urban dwelling (AOR 2.84, 95% CI 1.04– 7.78) were significantly associated with DR.Conclusion: One in every five DM patients had DR. Sociodemographic, anthropometric, and blood lipids were independently associated with DR. To reduce the burden of diabetes, strategies that focus on lifestyle modifications targeted at identified modifiable risk factors are essential.Keywords: diabetes mellitus, diabetic retinopathy, Ethiopiahttps://www.dovepress.com/prevalence-and-factors-associated-with-diabetic-retinopathy-among-adul-peer-reviewed-fulltext-article-OPTHdiabetes mellitusdiabetic retinopathyethiopia |
| spellingShingle | Sahiledengle B Assefa T Negash W Tahir A Regasa T Tekalegn Y Mamo A Teferu Z Solomon D Gezahegn H Bekele K Zenbaba D Tasew A Desta F Regassa Z Feleke Z Kene C Tolcha F Gomora D Dibaba D Atlaw D Prevalence and Factors Associated with Diabetic Retinopathy among Adult Diabetes Patients in Southeast Ethiopia: A Hospital-Based Cross-Sectional Study Clinical Ophthalmology diabetes mellitus diabetic retinopathy ethiopia |
| title | Prevalence and Factors Associated with Diabetic Retinopathy among Adult Diabetes Patients in Southeast Ethiopia: A Hospital-Based Cross-Sectional Study |
| title_full | Prevalence and Factors Associated with Diabetic Retinopathy among Adult Diabetes Patients in Southeast Ethiopia: A Hospital-Based Cross-Sectional Study |
| title_fullStr | Prevalence and Factors Associated with Diabetic Retinopathy among Adult Diabetes Patients in Southeast Ethiopia: A Hospital-Based Cross-Sectional Study |
| title_full_unstemmed | Prevalence and Factors Associated with Diabetic Retinopathy among Adult Diabetes Patients in Southeast Ethiopia: A Hospital-Based Cross-Sectional Study |
| title_short | Prevalence and Factors Associated with Diabetic Retinopathy among Adult Diabetes Patients in Southeast Ethiopia: A Hospital-Based Cross-Sectional Study |
| title_sort | prevalence and factors associated with diabetic retinopathy among adult diabetes patients in southeast ethiopia a hospital based cross sectional study |
| topic | diabetes mellitus diabetic retinopathy ethiopia |
| url | https://www.dovepress.com/prevalence-and-factors-associated-with-diabetic-retinopathy-among-adul-peer-reviewed-fulltext-article-OPTH |
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