Comparison of ‘time to detection’ values between BacT/ALERT VIRTUO and BacT/ALERT 3D instruments for clinical blood culture samples
Objectives: The early detection of bacteraemia and fungemia is of paramount importance to guide antimicrobial therapy in septic patients. In this study the ‘time to detection’ (TTD) value for the new blood culture system BacT/ALERT VIRTUO (VIRTUO) was evaluated in 1462 positive clinical bottles and...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2017-09-01
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| Series: | International Journal of Infectious Diseases |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1201971217301662 |
| _version_ | 1818963053808451584 |
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| author | Francesco Congestrì Maria Federica Pedna Michela Fantini Michela Samuelli Pasqua Schiavone Arianna Torri Stefania Bertini Vittorio Sambri |
| author_facet | Francesco Congestrì Maria Federica Pedna Michela Fantini Michela Samuelli Pasqua Schiavone Arianna Torri Stefania Bertini Vittorio Sambri |
| author_sort | Francesco Congestrì |
| collection | DOAJ |
| description | Objectives: The early detection of bacteraemia and fungemia is of paramount importance to guide antimicrobial therapy in septic patients. In this study the ‘time to detection’ (TTD) value for the new blood culture system BacT/ALERT VIRTUO (VIRTUO) was evaluated in 1462 positive clinical bottles and compared with the TTD for 1601 positive clinical bottles incubated in the BacT/ALERT 3D system (BTA-3D).
Methods: The most representative microorganisms isolated from bottles incubated in both blood culture systems were divided into eight categories (in order of frequency): coagulase-negative staphylococci (CoNS), Escherichia coli, Enterobacteriaceae (other than E. coli), Staphylococcus aureus, Enterococcus spp, viridans group streptococci, Pseudomonas aeruginosa, and Candida spp.
Results: The comparison of TTD values for the two blood culture systems strongly indicated that growth of the first five groups listed above was detected earlier with VIRTUO than with BTA-3D (p < 0.05).
Conclusions: The new VIRTUO blood culture system can reduce the TTD for more than 75% of isolated microorganisms. |
| first_indexed | 2024-12-20T12:39:06Z |
| format | Article |
| id | doaj.art-21c916bbbba6499d957bec6c4de6dfec |
| institution | Directory Open Access Journal |
| issn | 1201-9712 1878-3511 |
| language | English |
| last_indexed | 2024-12-20T12:39:06Z |
| publishDate | 2017-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | International Journal of Infectious Diseases |
| spelling | doaj.art-21c916bbbba6499d957bec6c4de6dfec2022-12-21T19:40:32ZengElsevierInternational Journal of Infectious Diseases1201-97121878-35112017-09-0162C1510.1016/j.ijid.2017.06.012Comparison of ‘time to detection’ values between BacT/ALERT VIRTUO and BacT/ALERT 3D instruments for clinical blood culture samplesFrancesco Congestrì0Maria Federica Pedna1Michela Fantini2Michela Samuelli3Pasqua Schiavone4Arianna Torri5Stefania Bertini6Vittorio Sambri7Unit of Microbiology, Greater Romagna Hub Laboratory, Pievesestina di Cesena, ItalyUnit of Microbiology, Greater Romagna Hub Laboratory, Pievesestina di Cesena, ItalyUnit of Microbiology, Greater Romagna Hub Laboratory, Pievesestina di Cesena, ItalyUnit of Microbiology, Greater Romagna Hub Laboratory, Pievesestina di Cesena, ItalyUnit of Microbiology, Greater Romagna Hub Laboratory, Pievesestina di Cesena, ItalyUnit of Microbiology, Greater Romagna Hub Laboratory, Pievesestina di Cesena, ItalyUnit of Microbiology, Greater Romagna Hub Laboratory, Pievesestina di Cesena, ItalyUnit of Microbiology, Greater Romagna Hub Laboratory, Pievesestina di Cesena, ItalyObjectives: The early detection of bacteraemia and fungemia is of paramount importance to guide antimicrobial therapy in septic patients. In this study the ‘time to detection’ (TTD) value for the new blood culture system BacT/ALERT VIRTUO (VIRTUO) was evaluated in 1462 positive clinical bottles and compared with the TTD for 1601 positive clinical bottles incubated in the BacT/ALERT 3D system (BTA-3D). Methods: The most representative microorganisms isolated from bottles incubated in both blood culture systems were divided into eight categories (in order of frequency): coagulase-negative staphylococci (CoNS), Escherichia coli, Enterobacteriaceae (other than E. coli), Staphylococcus aureus, Enterococcus spp, viridans group streptococci, Pseudomonas aeruginosa, and Candida spp. Results: The comparison of TTD values for the two blood culture systems strongly indicated that growth of the first five groups listed above was detected earlier with VIRTUO than with BTA-3D (p < 0.05). Conclusions: The new VIRTUO blood culture system can reduce the TTD for more than 75% of isolated microorganisms.http://www.sciencedirect.com/science/article/pii/S1201971217301662BacteraemiaSepsisBlood culture systemsMicroorganisms causing sepsisTime to detectionEarly sepsis detectionVIRTUO systemBacT/ALERT 3D system |
| spellingShingle | Francesco Congestrì Maria Federica Pedna Michela Fantini Michela Samuelli Pasqua Schiavone Arianna Torri Stefania Bertini Vittorio Sambri Comparison of ‘time to detection’ values between BacT/ALERT VIRTUO and BacT/ALERT 3D instruments for clinical blood culture samples International Journal of Infectious Diseases Bacteraemia Sepsis Blood culture systems Microorganisms causing sepsis Time to detection Early sepsis detection VIRTUO system BacT/ALERT 3D system |
| title | Comparison of ‘time to detection’ values between BacT/ALERT VIRTUO and BacT/ALERT 3D instruments for clinical blood culture samples |
| title_full | Comparison of ‘time to detection’ values between BacT/ALERT VIRTUO and BacT/ALERT 3D instruments for clinical blood culture samples |
| title_fullStr | Comparison of ‘time to detection’ values between BacT/ALERT VIRTUO and BacT/ALERT 3D instruments for clinical blood culture samples |
| title_full_unstemmed | Comparison of ‘time to detection’ values between BacT/ALERT VIRTUO and BacT/ALERT 3D instruments for clinical blood culture samples |
| title_short | Comparison of ‘time to detection’ values between BacT/ALERT VIRTUO and BacT/ALERT 3D instruments for clinical blood culture samples |
| title_sort | comparison of time to detection values between bact alert virtuo and bact alert 3d instruments for clinical blood culture samples |
| topic | Bacteraemia Sepsis Blood culture systems Microorganisms causing sepsis Time to detection Early sepsis detection VIRTUO system BacT/ALERT 3D system |
| url | http://www.sciencedirect.com/science/article/pii/S1201971217301662 |
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