Effects of combination of concentrated Kurozu supplementation and endurance training on mitochondrial enzyme activity and energy metabolism in mice
We examined the effects of endurance training with chronic pre-exercise concentrated Kurozu (black vinegar) supplementation on mitochondrial enzyme activity and energy metabolism in Institute of Cancer Research (ICR) mice. Mice were divided into a control group, an endurance training group, and an e...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Japanese Society of Physical Fitness and Sports Medicine
2024-03-01
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| Series: | Journal of Physical Fitness and Sports Medicine |
| Subjects: | |
| Online Access: | https://www.jstage.jst.go.jp/article/jpfsm/13/2/13_35/_pdf/-char/en |
| _version_ | 1797263716613357568 |
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| author | Suguru Nakano Kohei Seike Mai Banjo Yumiko Takahashi Kenya Takahashi Yoshiyuki Matsumoto Hideo Hatta |
| author_facet | Suguru Nakano Kohei Seike Mai Banjo Yumiko Takahashi Kenya Takahashi Yoshiyuki Matsumoto Hideo Hatta |
| author_sort | Suguru Nakano |
| collection | DOAJ |
| description | We examined the effects of endurance training with chronic pre-exercise concentrated Kurozu (black vinegar) supplementation on mitochondrial enzyme activity and energy metabolism in Institute of Cancer Research (ICR) mice. Mice were divided into a control group, an endurance training group, and an endurance training + concentrated Kurozu supplementation group. Mice were orally supplemented with water or concentrated Kurozu solution (500 mg/kg body weight/day) for 3 weeks. The mice in the training group were subjected to exercise on a treadmill (20–25 m/min × 30 min, five times/week) starting 30 min after the supplementation. The maximal activity of citrate synthase in the plantaris muscle in the endurance training + concentrated Kurozu supplementation group was significantly higher than that in the control group (p < 0.01). The maximal activity of β-hydroxyacyl coenzyme dehydrogenase (β-HAD) in the soleus muscle in the endurance training + concentrated Kurozu supplementation group was significantly higher than that in the other two groups (p < 0.05 for both). In the final week, significant negative correlation between blood lactate concentration after exercise and soleus β-HAD activity was observed. These findings suggest that endurance training with concentrated Kurozu supplementation increases mitochondrial enzyme activity and might enhance lipid metabolism during exercise. |
| first_indexed | 2024-04-25T00:17:26Z |
| format | Article |
| id | doaj.art-21cf1a4d9fd24bd3a59cf6ee2fe1baef |
| institution | Directory Open Access Journal |
| issn | 2186-8131 2186-8123 |
| language | English |
| last_indexed | 2024-04-25T00:17:26Z |
| publishDate | 2024-03-01 |
| publisher | Japanese Society of Physical Fitness and Sports Medicine |
| record_format | Article |
| series | Journal of Physical Fitness and Sports Medicine |
| spelling | doaj.art-21cf1a4d9fd24bd3a59cf6ee2fe1baef2024-03-13T00:17:54ZengJapanese Society of Physical Fitness and Sports MedicineJournal of Physical Fitness and Sports Medicine2186-81312186-81232024-03-01132354110.7600/jpfsm.13.35jpfsmEffects of combination of concentrated Kurozu supplementation and endurance training on mitochondrial enzyme activity and energy metabolism in miceSuguru Nakano0Kohei Seike1Mai Banjo2Yumiko Takahashi3Kenya Takahashi4Yoshiyuki Matsumoto5Hideo Hatta6Department of Sports Sciences, The University of TokyoDepartment of Sports Science, Kyushu Kyoritsu UniversityDepartment of Sports Sciences, The University of TokyoDepartment of Sports Sciences, The University of TokyoDepartment of Sports Sciences, The University of TokyoEgao Health LaboratoryDepartment of Sports Sciences, The University of TokyoWe examined the effects of endurance training with chronic pre-exercise concentrated Kurozu (black vinegar) supplementation on mitochondrial enzyme activity and energy metabolism in Institute of Cancer Research (ICR) mice. Mice were divided into a control group, an endurance training group, and an endurance training + concentrated Kurozu supplementation group. Mice were orally supplemented with water or concentrated Kurozu solution (500 mg/kg body weight/day) for 3 weeks. The mice in the training group were subjected to exercise on a treadmill (20–25 m/min × 30 min, five times/week) starting 30 min after the supplementation. The maximal activity of citrate synthase in the plantaris muscle in the endurance training + concentrated Kurozu supplementation group was significantly higher than that in the control group (p < 0.01). The maximal activity of β-hydroxyacyl coenzyme dehydrogenase (β-HAD) in the soleus muscle in the endurance training + concentrated Kurozu supplementation group was significantly higher than that in the other two groups (p < 0.05 for both). In the final week, significant negative correlation between blood lactate concentration after exercise and soleus β-HAD activity was observed. These findings suggest that endurance training with concentrated Kurozu supplementation increases mitochondrial enzyme activity and might enhance lipid metabolism during exercise.https://www.jstage.jst.go.jp/article/jpfsm/13/2/13_35/_pdf/-char/enendurance trainingmitochondria adaptationskeletal muscleconcentrated kurozu |
| spellingShingle | Suguru Nakano Kohei Seike Mai Banjo Yumiko Takahashi Kenya Takahashi Yoshiyuki Matsumoto Hideo Hatta Effects of combination of concentrated Kurozu supplementation and endurance training on mitochondrial enzyme activity and energy metabolism in mice Journal of Physical Fitness and Sports Medicine endurance training mitochondria adaptation skeletal muscle concentrated kurozu |
| title | Effects of combination of concentrated Kurozu supplementation and endurance training on mitochondrial enzyme activity and energy metabolism in mice |
| title_full | Effects of combination of concentrated Kurozu supplementation and endurance training on mitochondrial enzyme activity and energy metabolism in mice |
| title_fullStr | Effects of combination of concentrated Kurozu supplementation and endurance training on mitochondrial enzyme activity and energy metabolism in mice |
| title_full_unstemmed | Effects of combination of concentrated Kurozu supplementation and endurance training on mitochondrial enzyme activity and energy metabolism in mice |
| title_short | Effects of combination of concentrated Kurozu supplementation and endurance training on mitochondrial enzyme activity and energy metabolism in mice |
| title_sort | effects of combination of concentrated kurozu supplementation and endurance training on mitochondrial enzyme activity and energy metabolism in mice |
| topic | endurance training mitochondria adaptation skeletal muscle concentrated kurozu |
| url | https://www.jstage.jst.go.jp/article/jpfsm/13/2/13_35/_pdf/-char/en |
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