Efficient Predictor for Immunotherapy Efficacy: Detecting Pan‐Clones Effector Tumor Antigen‐Specific T Cells in Blood by Nanoparticles Loading Whole Tumor Antigens

Efficient Predictor for Immunotherapy Efficacy: Detecting Pan‐Clones Effector Tumor Antigen‐Specific T Cells in Blood by Nanoparticles Loading Whole Tumor Antigens

Abstract Cancer involves tumor cells and tumor‐specific immunity. The ability to accurately quantify tumor‐specific immunity is limited. Most immunotherapies function by activating new effector tumor antigen‐specific T cells (ETASTs) or reactivating the pre‐existing ETASTs repertoire. Therefore, the...

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Bibliographic Details
Main Authors: Weibiao Zeng, Jin Wang, Zhike Chen, Jian Yang, Ao Zhu, Yan Zheng, Xianlan Chen, Yuhan Liu, Leilei Wu, Yufeng Xie, Sheng Ju, Jun Chen, Cheng Ding, Chang Li, Xin Tong, Mi Liu, Jun Zhao
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Advanced Science
Subjects:
antigen‐specific T cells
biomarker
cancer
immunotherapy
tumor antigen
Online Access:https://doi.org/10.1002/advs.202409913

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