Heritable and lineage-specific gene knockdown in zebrafish embryo.

Heritable and lineage-specific gene knockdown in zebrafish embryo.

BACKGROUND: Reduced expression of developmentally important genes and tumor suppressors due to haploinsufficiency or epigenetic suppression has been shown to contribute to the pathogenesis of various malignancies. However, methodology that allows spatio-temporally knockdown of gene expression in var...

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Bibliographic Details
Main Authors: Mei Dong, Yan-Fang Fu, Ting-Ting Du, Chang-Bin Jing, Chun-Tang Fu, Yi Chen, Yi Jin, Min Deng, Ting Xi Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2702085?pdf=render

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